Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 3/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27096974 | 1.00 | MAP4K4 (0.41) | MAP4K4ALDH1A1HTTSLC2A1CCNC | |
| SCHEMBL27096932 | 0.82 | MALT1 (0.45) | CCNCCDK8KDM4EMAPTMALT1 | |
| SCHEMBL30885063 | 0.79 | MALT1 (0.44) | ALDH1A1KDM4EMAPTMALT1 | |
| SCHEMBL27309672 | 0.79 | MALT1 (0.44) | ALDH1A1KDM4EMAPTMALT1 | |
| SCHEMBL29834705 | 0.78 | MAP4K4 (0.43) | MAP4K4CCNCCDK8ACACBSCN10A | |
| SCHEMBL30729915 | 0.76 | NPC1 (0.46) | ALDH1A1CCNCCDK8KDM4EMAPT | |
| SCHEMBL29834832 | 0.74 | MAP4K4 (0.39) | MAP4K4ALDH1A1CCNCCDK8ACACB | |
| SCHEMBL16785630 | 0.70 | MAP4K4 (0.46) | MAP4K4KCNH2 | |
| SCHEMBL2415575 | 0.69 | PDE7A (0.42) | ALDH1A1KDM4EMAPTKCNH2 | |
| SCHEMBL20694232 | 0.69 | MALT1 (0.45) | ALDH1A1SCDKDM4EMAPTMALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026056-A2 | HETEROARYL COMPOUNDS AS EGFR INHIBITORS AND THEIR USES | ACCUTAR BIOTECHNOLOGY, INC. (US) | 2024-02-01 | — | — | WO | disclosed |