Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 10/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.39 |
| ▸ | GABRE | P78334 | 1/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.39 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31032154 | 0.84 | POLQ (0.56) | POLQSMN1; SMN2LDHADDTKDM4E | |
| SCHEMBL24501303 | 0.84 | POLQ (0.56) | POLQSMN1; SMN2LDHADDTKDM4E | |
| SCHEMBL27310395 | 0.79 | HDAC7 (0.45) | SMN1; SMN2ALDH1A1KDM4EHSD17B10SORT1 | |
| SCHEMBL28109275 | 0.79 | LDHA (0.57) | POLQALDH1A1GABRPGABRDGABRA1 | |
| SCHEMBL31032024 | 0.79 | GABRP (0.42) | POLQSMN1; SMN2ALDH1A1MAPK1GABRP | |
| SCHEMBL24769551 | 0.79 | GABRP (0.42) | POLQSMN1; SMN2ALDH1A1MAPK1GABRP | |
| SCHEMBL24770862 | 0.77 | POLQ (0.44) | POLQSMN1; SMN2ALDH1A1MAPK1GABRP | |
| SCHEMBL27310151 | 0.76 | ALDH1A1 (0.44) | POLQALDH1A1MAPK1KDM4E | |
| SCHEMBL24501138 | 0.76 | POLQ (0.53) | POLQALDH1A1LDHADDTKDM4E | |
| SCHEMBL30640140 | 0.76 | POLQ (0.53) | POLQALDH1A1LDHADDTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4602028-A1 | CBL-B MODULATORS AND USES THEREOF | Nimbus Clio, Inc. (US) | 2025-08-20 | — | — | EP | disclosed |
| WO-2024081311-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2024-04-18 | — | — | WO | disclosed |
| WO-2024081311-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2024-04-18 | — | — | WO | disclosed |