Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | AGER | Q15109 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31368527 | 0.81 | KDM4E (0.55) | KDM4ETDP1ALDH1A1NPSR1CYP3A4 | |
| SCHEMBL21449055 | 0.79 | KDM4E (0.57) | KDM4ETDP1ALDH1A1NPSR1CYP3A4 | |
| SCHEMBL5151972 | 0.77 | NAPRT (0.56) | KDM4ETDP1ALDH1A1NPSR1CYP3A4 | |
| SCHEMBL9826240 | 0.77 | LMNA (0.56) | KDM4ETDP1ALDH1A1NPSR1CYP3A4 | |
| SCHEMBL24351473 | 0.75 | NOS3 (0.41) | KDM4ESMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL6479557 | 0.75 | KMT2A (0.54) | KDM4ETDP1ALDH1A1NPSR1CYP3A4 | |
| SCHEMBL10516708 | 0.73 | KDM4E (0.46) | KDM4ETDP1ALDH1A1NPSR1CYP3A4 | |
| SCHEMBL71547 | 0.72 | KDM4E (0.63) | KDM4ETDP1ALDH1A1NPSR1CYP3A4 | |
| SCHEMBL29651292 | 0.72 | KDM4E (0.63) | KDM4ETDP1ALDH1A1NPSR1CYP3A4 | |
| SCHEMBL9712040 | 0.72 | F2 (0.55) | ALDH1A1ALOX15TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1033031-C | Modified gangliosides and functional derivatives thereof | FIDIA SPA (IT) | 1996-10-16 | — | — | CN | disclosed |
| CN-1051912-A | Improved gangliosides and functional derivatives thereof | FIDIA B P A (IT) | 1991-06-05 | — | — | CN | disclosed |