Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16504635 | 0.86 | LMNA (0.46) | HSD17B10LMNASMN1; SMN2KDM4EMAPT | |
| SCHEMBL7781973 | 0.82 | HSD17B10 (0.50) | HSD17B10LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL20412354 | 0.81 | HSD17B10 (0.54) | HSD17B10LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4324963 | 0.80 | ELANE (0.47) | HSD17B10CYP1A2KDM4EMAPTKMT2A | |
| SCHEMBL165007 | 0.80 | ELANE (0.47) | HSD17B10CYP1A2KDM4EMAPTKMT2A | |
| SCHEMBL809326 | 0.80 | ELANE (0.47) | HSD17B10CYP1A2KDM4EMAPTKMT2A | |
| SCHEMBL7268906 | 0.78 | ELANE (0.54) | HSD17B10LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3120830 | 0.78 | GSK3B (0.48) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL28914529 | 0.78 | GSK3B (0.48) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL7457988 | 0.78 | ELANE (0.44) | LMNAKDM4EMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1027504-C | Process for the preparation of imidazolyl-alkenoic acids | SMITHKLINE BEECHAM CORP (US) | 1995-01-25 | — | — | CN | disclosed |