Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7268906 | 0.83 | ELANE (0.54) | HSD17B10LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL20412354 | 0.82 | HSD17B10 (0.54) | HSD17B10LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL701147 | 0.82 | LMNA (0.58) | HSD17B10LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL27310554 | 0.82 | HSD17B10 (0.46) | HSD17B10LMNACYP1A2CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL2327786 | 0.80 | LMNA (0.56) | HSD17B10LMNACYP1A2CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL27539616 | 0.80 | LMNA (0.56) | HSD17B10LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL43236 | 0.77 | ELANE (0.52) | HSD17B10LMNACYP1A2KDM4EMAPT | |
| SCHEMBL20412357 | 0.77 | HSD17B10 (0.48) | HSD17B10LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL18727667 | 0.77 | HSD17B10 (0.58) | HSD17B10LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL13113097 | 0.76 | KMT2A (0.55) | LMNAKDM4EMAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722715-B1 | Cosmetic compositions containing lactate dehydrogenase inhibitors | UNILEVER PLC (GB) | 2001-10-24 | — | — | EP | claimed |
| US-5853742-A | Cosmetic compositions containing lactate dehydrogenase inhibitors | CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO (US) | 1998-12-29 | — | — | US | claimed |
| US-5690944-A | APPLYING TOPICALLY TO SKIN TO PREVENT WRINKLED AND AGED APPEARANCE | CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) | 1997-11-25 | — | — | US | claimed |
| EP-0722715-A1 | Cosmetic compositions containing lactate dehydrogenase inhibitors | UNILEVER PLC (GB) | 1996-07-24 | — | — | EP | claimed |
| JP-8231372-A | — | — | None | — | — | JP | disclosed |
| EP-0722715-B1 | Cosmetic compositions containing lactate dehydrogenase inhibitors | UNILEVER PLC (GB) | 2001-10-24 | — | — | EP | disclosed |
| US-5853742-A | Cosmetic compositions containing lactate dehydrogenase inhibitors | CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO (US) | 1998-12-29 | — | — | US | disclosed |
| US-5690944-A | APPLYING TOPICALLY TO SKIN TO PREVENT WRINKLED AND AGED APPEARANCE | CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) | 1997-11-25 | — | — | US | disclosed |
| JP-H08231372-A | COSMETIC COMPOSITION CONTAINING LACTATE DEHYDROGENASE INHIBITOR | UNILEVER NV | 1996-09-10 | — | — | JP | disclosed |
| EP-0722715-A1 | Cosmetic compositions containing lactate dehydrogenase inhibitors | UNILEVER PLC (GB) | 1996-07-24 | — | — | EP | disclosed |