Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27309537 | 0.84 | TDP1 (0.51) | KDM4EPTGDR2TDP1PTGDR | |
| SCHEMBL27310559 | 0.83 | KDM4E (0.53) | PKMKDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL9379799 | 0.83 | PKM (0.50) | PKMKDM4EPTGDR2ALDH1A1HPGD | |
| SCHEMBL29379589 | 0.80 | ACACA (0.53) | PKMKDM4EPTGDR2ALDH1A1HPGD | |
| SCHEMBL27325060 | 0.77 | TDP1 (0.52) | KDM4EPTGDR2ALDH1A1HPGDTDP1 | |
| SCHEMBL27322966 | 0.75 | KDM4E (0.52) | PKMKDM4EPTGDR2ALDH1A1HPGD | |
| SCHEMBL27561346 | 0.72 | CYSLTR2 (0.48) | KDM4EPTGDR2SMN1; SMN2PDE10ALMNA | |
| SCHEMBL9380016 | 0.71 | PKM (0.52) | PKMKDM4EPTGDR2ALDH1A1HPGD | |
| SCHEMBL5538132 | 0.71 | KDM4E (0.51) | PKMKDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL27344573 | 0.70 | KMT2A (0.47) | KDM4EPTGDR2ALDH1A1HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1027369-C | Excitatory amino acid antagonists | MERRELL DOW PHARMA (US) | 1995-01-11 | — | — | CN | disclosed |
| CN-1047292-A | EAA antagonists | MERRELL DOW PHARMA (US) | 1990-11-28 | — | — | CN | disclosed |