Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.40 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 8/20 | 0.32 |
| ▸ | ROS1 | P08922 | 2/20 | 0.31 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.31 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.31 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
| ▸ | PER2 | O15055 | 3/20 | 0.31 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27311626 | 1.00 | MAPKAPK2 (0.40) | MAPKAPK2RPS6KA3HRH3ALOX5AKR1B1 | |
| SCHEMBL27311469 | 0.77 | MAPKAPK2 (0.47) | MAPKAPK2RPS6KA3HRH3ALOX5 | |
| SCHEMBL27312679 | 0.77 | MAPKAPK2 (0.47) | MAPKAPK2RPS6KA3HRH3ALOX5 | |
| SCHEMBL30954512 | 0.77 | MAPKAPK2 (0.47) | MAPKAPK2RPS6KA3HRH3ALOX5 | |
| SCHEMBL30954513 | 0.77 | MAPKAPK2 (0.47) | MAPKAPK2RPS6KA3HRH3ALOX5 | |
| SCHEMBL27312316 | 0.74 | RPS6KA3 (0.38) | MAPKAPK2RPS6KA3HRH3 | |
| SCHEMBL27312769 | 0.71 | P2RX7 (0.32) | HRH3 | |
| SCHEMBL4751694 | 0.68 | HRH3 (0.52) | MAPKAPK2RPS6KA3HRH3ALOX5PER2 | |
| SCHEMBL16094005 | 0.65 | P2RX7 (0.47) | — | |
| SCHEMBL16094003 | 0.65 | P2RX7 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024118524-A1 | AZAINDOLE COMPOUNDS AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | CEREVEL THERAPEUTICS, LLC (US) | 2024-06-06 | — | — | WO | disclosed |
| WO-2024118524-A1 | AZAINDOLE COMPOUNDS AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | CEREVEL THERAPEUTICS, LLC (US) | 2024-06-06 | — | — | WO | disclosed |