Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | TDO2 | P48775 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MPI | P34949 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25327896 | 0.80 | OPRM1 (0.46) | BRD4IDO1TDO2KDM4EALDH1A1 | |
| SCHEMBL17179169 | 0.72 | ALDH1A1 (0.51) | BRD4IDO1TDO2KDM4EALDH1A1 | |
| SCHEMBL10907418 | 0.72 | BRD4 (0.55) | BRD4IDO1TDO2ALDH1A1GAA | |
| SCHEMBL17179417 | 0.71 | IDO1 (0.51) | BRD4IDO1TDO2KDM4EALDH1A1 | |
| SCHEMBL25329372 | 0.71 | ALDH1A1 (0.38) | BRD4IDO1TDO2KDM4EALDH1A1 | |
| SCHEMBL23618102 | 0.71 | BRD4 (0.40) | BRD4KDM4EALDH1A1GAAHTT | |
| SCHEMBL22915221 | 0.70 | ALDH1A1 (0.46) | BRD4IDO1TDO2KDM4EALDH1A1 | |
| SCHEMBL23618106 | 0.69 | ALDH1A1 (0.41) | BRD4KDM4EALDH1A1GAAHTT | |
| SCHEMBL21420112 | 0.68 | IDO1 (0.45) | BRD4IDO1TDO2KDM4EALDH1A1 | |
| SCHEMBL24728223 | 0.68 | ALDH1A1 (0.45) | BRD4IDO1TDO2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1050187-A | New quinoline compound and preparation method thereof | ICI PLC (GB) | 1991-03-27 | — | — | CN | disclosed |