Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 8/20 | 0.37 |
| ▸ | NPC1 | O15118 | 7/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | HPGDS | O60760 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10793104 | 0.82 | RARB (0.54) | RARBRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL803074 | 0.81 | TP53 (0.50) | RARBRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL7723530 | 0.80 | RARB (0.60) | RARBRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL8526877 | 0.79 | TP53 (0.48) | RARBRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL20364675 | 0.79 | SMN1; SMN2 (0.58) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL8713869 | 0.79 | RARB (0.62) | RARBRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL5888400 | 0.79 | RARB (0.62) | RARBRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL8747808 | 0.79 | RARB (0.62) | RARBRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL9272426 | 0.79 | RARB (0.62) | RARBRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL8631186 | 0.79 | RARB (0.62) | RARBRAB9ANPC1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1032435-A | The phenyl trifluoromethyl ethers that replaces | MERCK PATENT GMBH (DE) | 1989-04-19 | — | — | CN | disclosed |