Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27311684 | 0.85 | DRD2 (0.47) | FFAR1DRD2DRD4DRD3HSD17B1 | |
| SCHEMBL27682910 | 0.80 | DRD2 (0.49) | FFAR1DRD2DRD4DRD3PPARG | |
| SCHEMBL14209113 | 0.78 | LMNA (0.46) | FFAR1DRD2DRD4DRD3HSD17B1 | |
| SCHEMBL5111304 | 0.78 | FFAR1 (0.58) | FFAR1DRD2DRD4DRD3PPARG | |
| SCHEMBL5106193 | 0.77 | DRD2 (0.51) | FFAR1DRD2DRD4DRD3PPARG | |
| SCHEMBL8017084 | 0.76 | FFAR1 (0.50) | FFAR1PPARGPPARAGAATSHR | |
| SCHEMBL10455047 | 0.74 | ESR1 (0.67) | FFAR1MMP3BCL2L1ESR1ESR2 | |
| SCHEMBL7158031 | 0.73 | ESR1 (0.44) | HSD17B1HSD17B2ESR1ESR2 | |
| SCHEMBL3070107 | 0.73 | PTPN11 (0.50) | DRD2DRD4DRD3HSD17B1HSD17B2 | |
| SCHEMBL12844627 | 0.73 | DRD2 (0.51) | FFAR1DRD2DRD4DRD3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1028173-C | Process for preparing oxazole derivatives | BRISTOL MYERS SQUIBB CO (US) | 1995-04-12 | — | — | CN | disclosed |
| CN-1101043-A | Process for preparing oxazole derivatives | BRISTOL MYERS SQUIBB CO (US) | 1995-04-05 | — | — | CN | disclosed |
| CN-1101042-A | Process for preparing oxazole derivatives | BRISTOL MYERS SQUIBB CO (US) | 1995-04-05 | — | — | CN | disclosed |
| CN-1101041-A | Process for preparing oxazole derivatives | BRISTOL MYERS SQUIBB CO (US) | 1995-04-05 | — | — | CN | disclosed |
| CN-1052667-A | OXAZOLE DERIVATIVES | BRISTOL MYERS SQUIBB CO (US) | 1991-07-03 | — | — | CN | disclosed |