Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.47 |
| ▸ | DRD4 | P21917 | 3/20 | 0.47 |
| ▸ | DRD3 | P35462 | 3/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27314005 | 0.85 | FFAR1 (0.54) | DRD2DRD4DRD3HSD17B1HSD17B2 | |
| SCHEMBL27682910 | 0.77 | DRD2 (0.49) | DRD2DRD4DRD3FFAR1GAA | |
| SCHEMBL27309679 | 0.74 | PPARA (0.45) | DRD2DRD4DRD3FFAR1GAA | |
| SCHEMBL5106193 | 0.74 | DRD2 (0.51) | DRD2DRD4DRD3FFAR1GAA | |
| SCHEMBL8840174 | 0.72 | FFAR1 (0.50) | DRD2DRD4DRD3FFAR1GAA | |
| SCHEMBL5105819 | 0.72 | DRD2 (0.51) | DRD2DRD4DRD3FFAR1GAA | |
| SCHEMBL6474732 | 0.72 | HSD17B1 (0.57) | HSD17B1HSD17B2FFAR1PPARA | |
| 3-Phenethylphenol SCHEMBL717571 | 0.71 | OPRK1 (0.74) | DRD2DRD3OPRK1OPRM1OPRD1 | |
| SCHEMBL12844627 | 0.70 | DRD2 (0.51) | DRD2DRD4DRD3FFAR1 | |
| SCHEMBL2225947 | 0.70 | DRD2 (0.51) | DRD2DRD4DRD3FFAR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1028173-C | Process for preparing oxazole derivatives | BRISTOL MYERS SQUIBB CO (US) | 1995-04-12 | — | — | CN | disclosed |
| CN-1101043-A | Process for preparing oxazole derivatives | BRISTOL MYERS SQUIBB CO (US) | 1995-04-05 | — | — | CN | disclosed |
| CN-1101041-A | Process for preparing oxazole derivatives | BRISTOL MYERS SQUIBB CO (US) | 1995-04-05 | — | — | CN | disclosed |
| CN-1101042-A | Process for preparing oxazole derivatives | BRISTOL MYERS SQUIBB CO (US) | 1995-04-05 | — | — | CN | disclosed |
| CN-1052667-A | OXAZOLE DERIVATIVES | BRISTOL MYERS SQUIBB CO (US) | 1991-07-03 | — | — | CN | disclosed |