Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | KDM4B | O94953 | 2/20 | 0.39 |
| ▸ | KDM5C | P41229 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9529340 | 0.82 | ABL1 (0.46) | ALDH1A1MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL9530780 | 0.80 | ATP4A (0.39) | MAPTADORA3ADORA2ANPC1GFER | |
| SCHEMBL2642609 | 0.75 | PIK3CG (0.53) | PIK3CGALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL27400125 | 0.74 | TP53 (0.54) | PIK3CGALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL27400126 | 0.72 | PIK3CG (0.51) | PIK3CGALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL2380472 | 0.71 | PIK3CG (0.53) | PIK3CGALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL126387 | 0.71 | KMT2A (0.66) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL10868877 | 0.70 | PIK3CG (0.63) | PIK3CGALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9753194 | 0.70 | SORT1 (0.53) | ALDH1A1KDM4EADORA3ADORA2ANPC1 | |
| SCHEMBL10519259 | 0.70 | ALDH1A1 (0.60) | PIK3CGALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1050191-A | New thiazole derivative, they the preparation method and contain their pharmaceutical composition | FUJISAWA PHARMACEUTICAL CO (JP) | 1991-03-27 | — | — | CN | disclosed |