Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | FADS1 | O60427 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2825625 | 0.83 | GAA (0.50) | PARP1KMT2AALDH1A1POLBGAA | |
| SCHEMBL21772779 | 0.81 | FADS1 (0.40) | PARP1SLC2A1MEN1KMT2AALDH1A1 | |
| SCHEMBL23414973 | 0.80 | FADS1 (0.52) | PARP1SLC2A1MEN1KMT2AALDH1A1 | |
| SCHEMBL21772792 | 0.80 | ALDH1A1 (0.41) | PARP1SLC2A1MEN1KMT2AALDH1A1 | |
| SCHEMBL23456478 | 0.80 | FADS1 (0.41) | PARP1SLC2A1MEN1KMT2AALDH1A1 | |
| SCHEMBL29955989 | 0.77 | MAPT (0.63) | PARP1MEN1KMT2AALDH1A1POLB | |
| SCHEMBL5131549 | 0.76 | KDM4E (0.62) | MEN1KMT2AALDH1A1POLBGAA | |
| SCHEMBL3958536 | 0.75 | PABPC1 (0.46) | ALDH1A1POLBGAAFADS1PABPC1 | |
| SCHEMBL9203119 | 0.73 | PABPC1 (0.43) | PARP1ALDH1A1POLBGAAGABRA2 | |
| SCHEMBL21772731 | 0.72 | ALDH1A1 (0.41) | ALDH1A1POLBGAAKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543879-A1 | PROTACS FOR TARGETED DEGRADATION OF KAT2A AND KAT2B FOR THE TREATMENT OF CANCER | University College Cardiff Consultants Limited (GB) | 2025-04-30 | — | — | EP | disclosed |
| WO-2024003533-A1 | PROTACS FOR TARGETED DEGRADATION OF KAT2A AND KAT2B FOR THE TREATMENT OF CANCER | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2024-01-04 | — | — | WO | disclosed |
| WO-2024003533-A1 | PROTACS FOR TARGETED DEGRADATION OF KAT2A AND KAT2B FOR THE TREATMENT OF CANCER | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2024-01-04 | — | — | WO | disclosed |