Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8656564 | 0.81 | TDP1 (0.41) | ALDH1A1KDM4EMAPTMEN1CASP1 | |
| SCHEMBL27314727 | 0.79 | ALDH1A1 (0.37) | ALDH1A1KDM4EMAPTMEN1CASP1 | |
| SCHEMBL8653719 | 0.76 | HTT (0.35) | ALDH1A1KDM4EMAPTMEN1CASP1 | |
| SCHEMBL8654232 | 0.75 | POLB (0.41) | ALDH1A1KDM4EMAPTMEN1CASP1 | |
| SCHEMBL9834046 | 0.72 | MAPT (0.47) | ALDH1A1KDM4EMAPTMEN1CASP1 | |
| SCHEMBL8841799 | 0.72 | JAK3 (0.41) | ALDH1A1KDM4EMAPTMEN1CASP1 | |
| SCHEMBL8655676 | 0.72 | POLB (0.41) | ALDH1A1KDM4EMAPTMEN1CASP1 | |
| SCHEMBL8820335 | 0.72 | KCNMA1 (0.43) | ALDH1A1MAPTMEN1CASP1KMT2A | |
| SCHEMBL27346346 | 0.71 | TDP1 (0.35) | ALDH1A1KDM4EMAPTMEN1CASP1 | |
| SCHEMBL27374489 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1031053-C | Azaoxindole derivatives | PFIZER (US) | 1996-02-21 | — | — | CN | disclosed |
| CN-1053065-A | AZAOXINDOLE DERIVATIVES | PFIZER (US) | 1991-07-17 | — | — | CN | disclosed |