Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVRL1 | P37023 | 10/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 7/20 | 0.43 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | RICTOR | Q6R327 | 1/20 | 0.38 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.38 |
| ▸ | MAPKAP1 | Q9BPZ7 | 1/20 | 0.38 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27315078 | 0.84 | ACVRL1 (0.47) | ACVRL1PIK3CDTNK2 | |
| SCHEMBL22132915 | 0.82 | ACVRL1 (0.58) | ACVRL1PIK3CDMTORRICTORRPTOR | |
| SCHEMBL16655528 | 0.81 | PIK3CD (0.41) | ACVRL1PIK3CDTNK2MTORRICTOR | |
| SCHEMBL27315133 | 0.78 | ACVRL1 (0.45) | ACVRL1PIK3CDTNK2MTORRICTOR | |
| SCHEMBL29388440 | 0.78 | ACVRL1 (0.39) | ACVRL1PIK3CD | |
| SCHEMBL31391141 | 0.77 | ACVRL1 (0.49) | ACVRL1PIK3CDMTORRICTORRPTOR | |
| SCHEMBL22132768 | 0.77 | EGFR (0.45) | ACVRL1PIK3CD | |
| SCHEMBL22132857 | 0.76 | RIPK1 (0.46) | TNK2 | |
| SCHEMBL22132905 | 0.74 | RIPK1 (0.48) | PIK3CDTNK2 | |
| SCHEMBL22132863 | 0.74 | RIPK1 (0.48) | PIK3CDTNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4611900-A1 | RET-LDD PROTEIN INHIBITORS | Bristol-Myers Squibb Company (US) | 2025-09-10 | — | — | EP | disclosed |
| WO-2024097980-A1 | RET-LDD PROTEIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-05-10 | — | — | WO | disclosed |
| WO-2024097980-A1 | RET-LDD PROTEIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-05-10 | — | — | WO | disclosed |