Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVRL1 | P37023 | 10/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.37 |
| ▸ | PDE2A | O00408 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | MERTK | Q12866 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27315079 | 0.78 | ACVRL1 (0.46) | ACVRL1PIK3CD | |
| SCHEMBL22132768 | 0.74 | EGFR (0.45) | ACVRL1PIK3CD | |
| SCHEMBL22132863 | 0.74 | RIPK1 (0.48) | PIK3CDAXLMERTK | |
| SCHEMBL22132905 | 0.74 | RIPK1 (0.48) | PIK3CDAXLMERTK | |
| SCHEMBL22132930 | 0.74 | RIPK1 (0.48) | PIK3CDAXLMERTK | |
| SCHEMBL22132770 | 0.73 | ACVRL1 (0.41) | ACVRL1PIK3CDPDE2ATYRO3AXL | |
| SCHEMBL22132915 | 0.72 | ACVRL1 (0.58) | ACVRL1PIK3CDTYRO3 | |
| SCHEMBL22132857 | 0.71 | RIPK1 (0.46) | PDE2A | |
| SCHEMBL19377685 | 0.70 | TYRO3 (0.49) | ACVRL1TYRO3AXLMERTK | |
| SCHEMBL19377744 | 0.70 | TYRO3 (0.50) | ACVRL1TYRO3AXLMERTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022033532-A1 | FGFR AND MUTATION INHIBITOR THEREOF, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海和誉生物医药科技有限公司 | 2022-02-17 | — | — | WO | disclosed |