Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 12/20 | 0.54 |
| ▸ | IKZF3 | Q9UKT9 | 10/20 | 0.54 |
| ▸ | IKZF1 | Q13422 | 3/20 | 0.52 |
| ▸ | IKZF2 | Q9UKS7 | 3/20 | 0.48 |
| ▸ | TNF | P01375 | 2/20 | 0.44 |
| ▸ | IL1B | P01584 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27315739 | 0.89 | CRBN (0.53) | CRBNIKZF3IKZF1IKZF2TNF | |
| SCHEMBL27317316 | 0.88 | CRBN (0.52) | CRBNIKZF1IKZF2 | |
| SCHEMBL27320532 | 0.88 | CRBN (0.51) | CRBNIKZF3IKZF1IKZF2 | |
| SCHEMBL27313558 | 0.86 | CRBN (0.51) | CRBNIKZF3IKZF1IKZF2TNF | |
| SCHEMBL27316089 | 0.85 | CRBN (0.56) | CRBNIKZF3IKZF1IKZF2 | |
| SCHEMBL27217151 | 0.84 | CRBN (0.60) | CRBNIKZF1IKZF2 | |
| SCHEMBL27316193 | 0.84 | CRBN (0.55) | CRBNIKZF3IKZF1IKZF2 | |
| SCHEMBL27311194 | 0.84 | IKZF2 (0.52) | CRBNIKZF3IKZF1IKZF2 | |
| SCHEMBL27317312 | 0.84 | CRBN (0.59) | CRBNIKZF1IKZF2 | |
| SCHEMBL27317136 | 0.83 | CRBN (0.59) | CRBNIKZF3IKZF1IKZF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054832-A1 | CK1α AND DUAL CK1α / GSPT1 DEGRADING COMPOUNDS | INNOVO THERAPEUTICS, INC. (US) | 2024-03-14 | — | — | WO | disclosed |