Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL9421374 | 0.94 | TDP1 (0.67) | TDP1TSHRALDH1A1LMNA | |
| Propylene Glycol SCHEMBL78770 | 0.94 | — | — | |
| Propylene Glycol SCHEMBL10407640 | 0.94 | — | — | |
| Dioxane SCHEMBL28127315 | 0.91 | TDP1 (0.62) | TDP1TSHRALDH1A1LMNA | |
| Propylene Glycol SCHEMBL27397419 | 0.84 | — | — | |
| Tetrahydrofuran SCHEMBL10660627 | 0.83 | TDP1 (0.53) | TDP1TSHRALDH1A1 | |
| Glycerin SCHEMBL28000527 | 0.82 | LMNA (0.53) | TDP1TSHRALDH1A1LMNA | |
| Propylene Glycol SCHEMBL27778486 | 0.80 | — | — | |
| Tetrahydrofuran SCHEMBL4133541 | 0.80 | TDP1 (0.56) | TDP1TSHRALDH1A1 | |
| Propylene Glycol SCHEMBL9580858 | 0.79 | TDP1 (0.48) | TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1039281-C | Improved shampoo compositions | PROECTER & GAMBLE CO (US) | 1998-07-29 | — | — | CN | disclosed |
| CN-1061150-A | IMPROVED SHAMPOO COMPOSITIONS | PROCTER & GAMBLE (US) | 1992-05-20 | — | — | CN | disclosed |