SCHEMBL27317152

SCHEMBL27317152

CC[S+]([O-])c1ccccc1C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.35
NOS3 P29474 2/20 0.35
NOS1 P29475 2/20 0.35
NOS2 P35228 2/20 0.35
POLB P06746 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
ALDH1A1 P00352 2/20 0.33
MAPK1 P28482 1/20 0.33
HSD11B1 P28845 1/20 0.33
ESR1 P03372 1/20 0.33
MAOB P27338 2/20 0.33
MAOA P21397 1/20 0.33
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
CA2 P00918 1/20 0.32
POLQ O75417 1/20 0.31
PDK2 Q15119 1/20 0.31
LMNA P02545 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16019347 0.79 ALDH1A1 (0.32) TDP1ALDH1A1
SCHEMBL514109 0.78 ALDH1A1 (0.36) IDO1POLBTDP1L3MBTL1ALDH1A1
SCHEMBL3682424 0.77 ALDH1A1 (0.39) IDO1POLBTDP1L3MBTL1ALDH1A1
SCHEMBL777552 0.75 ACHE (0.37) IDO1L3MBTL1
SCHEMBL28149024 0.74
SCHEMBL3190148 0.72 ALDH1A1 (0.41) IDO1POLBTDP1L3MBTL1ALDH1A1
SCHEMBL11251707 0.72 CTNNB1 (0.40) TDP1ALDH1A1LMNAGAA
SCHEMBL9953786 0.71 P2RX7 (0.35)
SCHEMBL3882276 0.71 ACHE (0.39) TDP1ALDH1A1CA2
SCHEMBL1964790 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1034932-C Herbicides RHONE POULENC AGRICULTURE (GB) 1997-05-21 CN disclosed