SCHEMBL27317367

SCHEMBL27317367

CC(C#N)c1cc(=O)[nH]c(=O)[nH]1

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.42
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
CYP1A2 P05177 1/20 0.34
UPP1 Q16831 1/20 0.33
YTHDF3 Q7Z739 1/20 0.33
YTHDF1 Q9BYJ9 1/20 0.33
YTHDF2 Q9Y5A9 1/20 0.33
KDM4E B2RXH2 1/20 0.33
RECQL P46063 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
GPR84 Q9NQS5 7/20 0.33
SMN1; SMN2 Q16637 1/20 0.30
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28263698 0.74 CA1 (0.46) CA1ALDH1A1LMNACYP1A2YTHDF3
SCHEMBL27661275 0.69 ALDH1A1 (0.45) CA1ALDH1A1LMNACYP1A2YTHDF3
SCHEMBL14123299 0.64 CA1 (0.44) CA1ALDH1A1LMNACYP1A2UPP1
SCHEMBL4625741 0.63 LMNA (0.48) CA1ALDH1A1LMNACYP1A2YTHDF3
SCHEMBL5688062 0.61 YTHDF3 (0.46) CA1ALDH1A1LMNACYP1A2YTHDF3
SCHEMBL60308 0.60
SCHEMBL28943111 0.60 CA1 (0.45) CA1ALDH1A1LMNACYP1A2YTHDF3
SCHEMBL10130747 0.60 GPR84 (0.50) CA1ALDH1A1GPR84SMN1; SMN2
SCHEMBL27906010 0.60 TSHR (0.36) CA1ALDH1A1
Acetonitrile SCHEMBL27753658 0.60 CA1 (0.35) CA1ALDH1A1CYP1A2UPP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024102986-A2 SARS-COV-2 MPRO INHIBITORS THE TEXAS A&M UNIVERSITY SYSTEM (US) 2024-05-16 WO disclosed