Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.46 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.46 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.46 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.46 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.46 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.46 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.46 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.46 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.46 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.46 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.46 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25311659 | 0.87 | PKM (0.53) | MEN1KMT2AALDH1A1POLBMAPT | |
| SCHEMBL25314500 | 0.86 | MEN1 (0.38) | MEN1KMT2ASMN1; SMN2TSHRABCG2 | |
| SCHEMBL10876059 | 0.86 | ABCG2 (0.53) | MEN1KMT2ASMN1; SMN2TSHRABCG2 | |
| SCHEMBL20970601 | 0.84 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1MAPTTNFRSF1A | |
| SCHEMBL8148063 | 0.84 | MEN1 (0.61) | MEN1KMT2ASMN1; SMN2TSHRABCG2 | |
| SCHEMBL17368848 | 0.80 | TSHR (0.33) | MEN1KMT2ASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL11832592 | 0.80 | HTR1A (0.62) | SMN1; SMN2ABCG2ALDH1A1TUBB1HTT | |
| SCHEMBL28872919 | 0.80 | KMT2A (0.58) | MEN1KMT2AABCG2ALDH1A1POLB | |
| SCHEMBL9311035 | 0.79 | MEN1 (0.53) | MEN1KMT2ASMN1; SMN2TSHRABCG2 | |
| SCHEMBL7123362 | 0.79 | MEN1 (0.56) | MEN1KMT2ASMN1; SMN2TSHRABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1062562-C | Corticosteroid 17-alkyl carbonate 21-[O]-carboxylic and carbonic esters, processes for their preparation, and pharmaceuticals containing these compounds | HOECHST AG (DE) | 2001-02-28 | — | — | CN | disclosed |
| CN-1056151-C | 17-deoxycorticosteroid-21-[O]-carboxylic esters, processes for their preparation and pharmaceuticals containing these compounds | HOECHST AG (DE) | 2000-09-06 | — | — | CN | disclosed |
| CN-1051316-C | Corticoid 17,21-dicarboxylic esters and corticosteroid 17-carboxylic ester 21-carbonic esters, processes for their preparation and pharmaceuticals containing these compounds | HOECHST AG (DE) | 2000-04-12 | — | — | CN | disclosed |
| CN-1124250-A | 17-deoxycorticosteroid-21-[O]-carboxylic esters, processes for their preparation and pharmaceuticals containing these compounds | HOECHST AG (DE) | 1996-06-12 | — | — | CN | disclosed |
| CN-1108661-A | Corticoid 17,21-dicarboxylic esters and corticosteroid 17-carboxylic ester 21-carbonic esters, processes for their preparation and pharmaceuticals containing these compounds | HOECHST AG (DE) | 1995-09-20 | — | — | CN | disclosed |
| CN-1105368-A | Corticosteroid 17-alkyl carbonate 21-[O]-carboxylic and carbonic esters, processes for their preparation, and pharmaceuticals containing these compounds | HOECHST AG (DE) | 1995-07-19 | — | — | CN | disclosed |