Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 3/20 | 0.44 |
| ▸ | HTR4 | Q13639 | 5/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 3/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27911632 | 0.84 | KCNJ1 (0.45) | PTGER4FDFT1KCNH2 | |
| SCHEMBL27894380 | 0.81 | PRMT1 (0.64) | PTGER4HTR4PRMT1HRH3 | |
| Tert-Butyl Formate SCHEMBL27322970 | 0.74 | PTGER4 (0.45) | PTGER4ALOX15PRMT1 | |
| SCHEMBL15681643 | 0.71 | PTGER4 (0.55) | PTGER4HTR4ALOX15PRMT1FDFT1 | |
| SCHEMBL27319005 | 0.69 | SLC18A3 (0.47) | L3MBTL1 | |
| SCHEMBL28290347 | 0.68 | HRH3 (0.46) | PTGER4HTR4PRMT1L3MBTL1HRH3 | |
| SCHEMBL27626856 | 0.68 | SLC18A3 (0.44) | HTR2B | |
| Ethoxycarbonyl Group SCHEMBL27894381 | 0.67 | PRMT1 (0.57) | PTGER4ALOX15PRMT1L3MBTL1 | |
| SCHEMBL6197542 | 0.67 | FDFT1 (0.50) | FDFT1KCNH2HRH3 | |
| SCHEMBL16577145 | 0.67 | ALOX15 (0.75) | PTGER4HTR4ALOX15CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1051308-C | Oxazolidin-2-one derivatives | HOFFMANN LA ROCHE (CH) | 2000-04-12 | — | — | CN | disclosed |
| CN-1109054-A | Oxazolidin-2-one derivatives | HOFFMANN LA ROCHE (CH) | 1995-09-27 | — | — | CN | disclosed |