Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8986471 | 0.79 | MAPT (0.58) | LMNAPOLBALDH1A1MAPTHPGD | |
| Ethoxycarbonyl Group SCHEMBL27319006 | 0.79 | NAMPT (0.46) | — | |
| SCHEMBL7300880 | 0.76 | LMNA (0.49) | SLC18A3LMNAPOLBALDH1A1MAPT | |
| SCHEMBL8986418 | 0.76 | LMNA (0.61) | LMNAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL10813817 | 0.76 | LMNA (0.61) | LMNAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL27322968 | 0.74 | LMNA (0.47) | SLC18A3LMNAPOLBMAPTHPGD | |
| SCHEMBL8986417 | 0.73 | NAMPT (0.65) | LMNAPOLBALDH1A1MAPTL3MBTL1 | |
| SCHEMBL17340327 | 0.73 | RAB9A (0.57) | LMNAALDH1A1MAPTL3MBTL1TP53 | |
| Tert-Butyl Formate SCHEMBL27322969 | 0.72 | NAMPT (0.44) | — | |
| SCHEMBL27863970 | 0.72 | HRH3 (0.52) | SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1051308-C | Oxazolidin-2-one derivatives | HOFFMANN LA ROCHE (CH) | 2000-04-12 | — | — | CN | disclosed |
| CN-1109054-A | Oxazolidin-2-one derivatives | HOFFMANN LA ROCHE (CH) | 1995-09-27 | — | — | CN | disclosed |