SCHEMBL27319871

SCHEMBL27319871

N#Cc1ccc(C(F)(F)F)c(C#N)c1N

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AR P10275 20/20 0.42
PGR P06401 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7920588 0.81 KIF11 (0.42) ARPGR
SCHEMBL25983203 0.79 KIF11 (0.44) AR
SCHEMBL25983164 0.78 AR (0.51) AR
SCHEMBL27414564 0.75 ALDH1A1 (0.46)
SCHEMBL15846053 0.75 KDM4E (0.47) ARPGR
SCHEMBL25983162 0.74 AR (0.47) ARPGR
SCHEMBL3657863 0.74 AR (0.45) ARPGR
SCHEMBL7868327 0.72 AR (0.46) ARPGR
SCHEMBL7625945 0.71 AR (0.40) AR
SCHEMBL28597079 0.71 KDM4E (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1046526-A New compound and preparation method thereof ICI PLC (GB) 1990-10-31 CN claimed
CN-1046526-A New compound and preparation method thereof ICI PLC (GB) 1990-10-31 CN disclosed