Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TYR | P14679 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PHGDH | O43175 | 3/20 | 0.44 |
| ▸ | SCD | O00767 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL703145 | 0.86 | RAB9A (0.60) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL4757285 | 0.76 | RAB9A (0.64) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL4757970 | 0.74 | NPC1 (0.65) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL4757221 | 0.73 | NPC1 (0.48) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL4757029 | 0.73 | RAB9A (0.50) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL4757279 | 0.73 | RRM1 (0.62) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL25290573 | 0.72 | KMT2A (0.50) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL2698148 | 0.72 | MAPT (0.55) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL704070 | 0.72 | KDM4A (0.54) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL3692973 | 0.71 | RAB9A (0.54) | MAPTRAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2635124-A1 | ALKYLSULFINYL-SUBSTITUTED THIAZOLIDE COMPOUNDS | Romark Laboratories, L.C. (US) | 2013-09-11 | — | — | EP | disclosed |
| WO-2012061190-A1 | ALKYLSULFINYL-SUBSTITUTED THIAZOLIDE COMPOUNDS | ROMARK LABORATORIES L.C. (US) | 2012-05-10 | — | — | WO | disclosed |