Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 12/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.43 |
| ▸ | MPO | P05164 | 5/20 | 0.40 |
| ▸ | HTR7 | P34969 | 5/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ICMT | O60725 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27319956 | 1.00 | HTR1A (0.43) | HTR1ASLC6A4MPOHTR7HTR2A | |
| SCHEMBL31534072 | 0.93 | CDK4 (0.43) | HTR1ASLC6A4KMT2A | |
| SCHEMBL31534055 | 0.93 | MPO (0.42) | HTR1ASLC6A4MPOHTR2ATRPM8 | |
| SCHEMBL27320817 | 0.93 | MPO (0.42) | HTR1ASLC6A4MPOHTR2ATRPM8 | |
| SCHEMBL30867157 | 0.90 | MPO (0.42) | HTR1ASLC6A4MPOHTR2ATRPM8 | |
| SCHEMBL27319951 | 0.90 | MPO (0.42) | HTR1ASLC6A4MPOHTR2ATRPM8 | |
| SCHEMBL27320810 | 0.87 | SNCA (0.41) | HTR1ASLC6A4MPOHTR2ATRPM8 | |
| SCHEMBL30867161 | 0.87 | SNCA (0.41) | HTR1ASLC6A4MPOHTR2ATRPM8 | |
| SCHEMBL30867191 | 0.86 | SNCA (0.40) | HTR1ASLC6A4HTR2ATRPM8 | |
| SCHEMBL31534096 | 0.85 | GSK3B (0.39) | HTR1ASLC6A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4598931-A1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2025-08-13 | — | — | EP | disclosed |
| CN-119948035-A | Compounds useful for modulating AhR signaling | 捷豹治疗有限公司 | 2025-05-06 | — | — | CN | disclosed |
| WO-2024076300-A1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2024-04-11 | — | — | WO | disclosed |