SCHEMBL27320995

SCHEMBL27320995

O=Cc1cnc(-c2ccccc2)c(Cl)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HPGD P15428 3/20 0.44
▸ ALDH1A1 P00352 6/20 0.41
▸ MEN1 O00255 2/20 0.39
▸ KMT2A Q03164 2/20 0.39
▸ PTGER4 P35408 1/20 0.39
▸ CYP2A6 P11509 1/20 0.39
▸ ADORA2A P29274 1/20 0.38
▸ GSR P00390 1/20 0.38
▸ L3MBTL1 Q9Y468 2/20 0.37
▸ TDP1 Q9NUW8 2/20 0.37
▸ ADORA1 P30542 1/20 0.37
▸ CYP1A2 P05177 1/20 0.37
▸ MAPT P10636 1/20 0.37
▸ CYP2C9 P11712 1/20 0.37
▸ CYP2C19 P33261 1/20 0.37
▸ HTT P42858 1/20 0.37
▸ DYRK3 O43781 1/20 0.37
▸ CCNT1 O60563 1/20 0.37
▸ CDK9 P50750 1/20 0.37
▸ CDK5 Q00535 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4162924 0.79 ALDH1A1 (0.42) ALDH1A1MEN1KMT2AL3MBTL1MAPT
SCHEMBL3610675 0.78 HDAC1 (0.51) HPGDALDH1A1MEN1KMT2ATDP1
SCHEMBL13741782 0.77 NPC1 (0.52) HPGDALDH1A1MEN1KMT2ATDP1
SCHEMBL8550043 0.76 ALDH1A1 (0.39) ALDH1A1MEN1KMT2APTGER4CYP2A6
SCHEMBL23300377 0.76 ALDH1A1 (0.53) HPGDALDH1A1ADORA2AL3MBTL1TDP1
SCHEMBL4156248 0.73 ADH5 (0.36) ALDH1A1MEN1KMT2AMAPT
SCHEMBL363943 0.73 ADORA2A (0.48) HPGDALDH1A1MEN1KMT2AADORA2A
SCHEMBL28182737 0.73 ALDH1A1 (0.44) HPGDALDH1A1MEN1KMT2AADORA2A
SCHEMBL4166189 0.72 HPGD (0.44) HPGDMEN1KMT2AADORA2A
SCHEMBL116316 0.71 ALDH1A1 (0.46) ALDH1A1L3MBTL1TDP1MAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070901-A1 NOVEL COMPOUNDS AS CK2 INHIBITORS CAMBRIDGE ENTPR LTD (GB) 2026-03-12 — — US disclosed
WO-2024052692-A1 NOVEL COMPOUNDS AS CK2 INHIBITORS CAMBRIDGE ENTERPRISE LIMITED (GB) 2024-03-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070901-A1 NOVEL COMPOUNDS AS CK2 INHIBITORS CSNK1A1, CSNK2A3, CSNK1G1 HPGD 3870/4885ALDH1A1 3874/4885MEN1 4295/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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