SCHEMBL27321985

SCHEMBL27321985

CCOC(=O)c1[nH]nc(N)c1SC(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.44
HPGD P15428 3/20 0.44
HTT P42858 2/20 0.44
ALDH1A1 P00352 2/20 0.44
RECQL P46063 1/20 0.44
ALOX15 P16050 1/20 0.41
KMT2A Q03164 2/20 0.39
MAPT P10636 2/20 0.39
POLB P06746 1/20 0.39
HSD17B10 Q99714 1/20 0.39
MAPK10 P53779 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
PDE4D Q08499 1/20 0.39
MEN1 O00255 1/20 0.38
CYP1A2 P05177 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
LMNA P02545 2/20 0.36
PKM P14618 1/20 0.35
IDO1 P14902 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8474076 0.84 KDM4C (0.41) ALDH1A1MAPTHSD17B10LMNA
SCHEMBL8842655 0.81
SCHEMBL599593 0.76 ALDH1A1 (0.54) KDM4EHPGDHTTALDH1A1RECQL
SCHEMBL7711653 0.74 KDM4E (0.43) KDM4EHPGDHTTALDH1A1RECQL
SCHEMBL10717172 0.72 KDM4E (0.48) KDM4EHPGDHTTALDH1A1RECQL
SCHEMBL4125363 0.70 SMN1; SMN2 (0.50) KDM4EHPGDHTTALDH1A1RECQL
SCHEMBL7715367 0.70 HPGD (0.48) KDM4EHPGDHTTALDH1A1RECQL
SCHEMBL31278376 0.70 KDM4E (0.48) KDM4EHPGDHTTALDH1A1RECQL
SCHEMBL18209960 0.69 PDE4D (0.56) KDM4EHPGDHTTALDH1A1RECQL
SCHEMBL13365026 0.69 KDM4E (0.50) KDM4EHPGDHTTALDH1A1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1027341-C N-Phenylpyrazole Derivative Insecticides MAY & BAKER LTD (FR) 1995-01-11 CN disclosed
CN-88103601-A N-PHENYLPYRAZOLE DERIVATIVES 1988-12-28 CN disclosed