Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7711653 | 0.83 | KDM4E (0.43) | HPGDALDH1A1HTTKDM4ERECQL | |
| SCHEMBL599593 | 0.79 | ALDH1A1 (0.54) | HPGDALDH1A1HTTKDM4ERECQL | |
| SCHEMBL17966217 | 0.73 | ALDH1A1 (0.47) | HPGDALDH1A1HTTKDM4ERECQL | |
| SCHEMBL31278376 | 0.73 | KDM4E (0.48) | HPGDALDH1A1HTTKDM4ERECQL | |
| SCHEMBL600955 | 0.72 | PDE4D (0.71) | HPGDALDH1A1HTTKDM4ERECQL | |
| SCHEMBL18209960 | 0.72 | PDE4D (0.56) | HPGDALDH1A1HTTKDM4ERECQL | |
| SCHEMBL27321985 | 0.70 | KDM4E (0.44) | HPGDALDH1A1HTTKDM4ERECQL | |
| SCHEMBL30964220 | 0.69 | MAPT (0.49) | HPGDALDH1A1HTTKDM4ERECQL | |
| SCHEMBL942577 | 0.69 | PDE4D (0.56) | HPGDALDH1A1HTTKDM4ERECQL | |
| SCHEMBL27140315 | 0.68 | PDE4D (0.59) | HPGDALDH1A1HTTKDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372774-B1 | THESE COMPOUNDS POSSESS ARTHROPODICIDAL, PLANT NEMATOCIDAL, ANTHELMINTIC AND ANTI-PROTOZOAL PROPERTIES | RHONE-POULENC AGRICULTURE LTD. (GB) | 2002-04-16 | — | — | US | disclosed |