Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | TACR1 | P25103 | 2/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TPMT | P51580 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL199862 | 0.85 | CYP3A4 (0.32) | TSHRCYP3A4 | |
| SCHEMBL18345630 | 0.80 | FFAR1 (0.33) | CYP3A4 | |
| SCHEMBL151739 | 0.79 | MIF (0.44) | IDO1L3MBTL1 | |
| SCHEMBL3924560 | 0.79 | HTR3E (0.52) | IDO1GRIN2BCYP3A4 | |
| SCHEMBL30483624 | 0.79 | HTR3E (0.52) | IDO1GRIN2BCYP3A4 | |
| SCHEMBL459297 | 0.76 | PGK1 (0.40) | GRIN2BCYP3A4 | |
| SCHEMBL27705400 | 0.76 | PGK1 (0.35) | TSHRGRIN2BTPMTCYP3A4 | |
| SCHEMBL28709411 | 0.76 | MIF (0.52) | TSHRIDO1GRIN1GRIN2BCYP3A4 | |
| SCHEMBL459983 | 0.76 | — | — | |
| SCHEMBL29384068 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117285890-A | Preparation method of formaldehyde-free environment-friendly flame-retardant plywood | 南宁市匠心鸣居建筑材料有限公司 | 2023-12-26 | — | — | CN | claimed |
| CN-115724772-B | Compound with urea structure, and preparation and application thereof | 云南大学 | 2024-08-02 | — | — | CN | disclosed |
| CN-116970011-B | Sulfonamide compound containing ureido structure and preparation method and application thereof | 沈阳药科大学 | 2024-05-10 | — | — | CN | disclosed |
| CN-117980066-A | Method for producing stationary phase for column chromatography | 株式会社大赛璐 | 2024-05-03 | — | — | CN | disclosed |
| CN-116082195-B | Pleuromutilin urea compounds, and preparation method and application thereof | 中国医学科学院药物研究所 | 2024-03-26 | — | — | CN | disclosed |
| CN-117343032-A | Method for preparing amide compound based on photocatalytic isocyanate | 中国科学技术大学 | 2024-01-05 | — | — | CN | disclosed |
| CN-114634449-B | Preparation method of 3- (3, 5-dichlorophenyl) -2, 4-imidazolidinedione | 北京颖泰嘉和生物科技股份有限公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-114634449-B | Preparation method of 3- (3, 5-dichlorophenyl) -2, 4-imidazolidinedione | 北京颖泰嘉和生物科技股份有限公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-116966885-A | Bonding type polysaccharide chiral stationary phase and preparation method and application thereof | 中国科学院化学研究所 | 2023-10-31 | — | — | CN | disclosed |
| CN-116970011-A | Sulfonamide compound containing ureido structure and preparation method and application thereof | 沈阳药科大学 | 2023-10-31 | — | — | CN | disclosed |
| US-9273028-B2 | Heterocyclic tyrosine kinase inhibitors | BIOGEN MA INC. (US) | 2016-03-01 | — | — | US | disclosed |
| US-9273028-B2 | Heterocyclic tyrosine kinase inhibitors | BIOGEN MA INC. (US) | 2016-03-01 | — | — | US | disclosed |
| US-9273028-B2 | Heterocyclic tyrosine kinase inhibitors | BIOGEN MA INC. (US) | 2016-03-01 | — | — | US | disclosed |
| US-20130345192-A1 | HETEROCYCLIC TYROSINE KINASE INHIBITORS | SUNESIS PHARMACEUTICALS, INC. (US) | 2013-12-26 | — | — | US | disclosed |
| EP-2632898-A1 | HETEROCYCLIC TYROSINE KINASE INHIBITORS | Biogen Idec MA Inc. (US) | 2013-09-04 | — | — | EP | disclosed |
| WO-2012058645-A1 | HETEROCYCLIC TYROSINE KINASE INHIBITORS | BIOGEN IDEC MA INC. (US) | 2012-05-03 | — | — | WO | disclosed |
| WO-2012058645-A1 | HETEROCYCLIC TYROSINE KINASE INHIBITORS | BIOGEN IDEC MA INC. (US) | 2012-05-03 | — | — | WO | disclosed |
| US-6417218-B1 | HT3 ANTAGONIST OR ANTIHISTAMINES | NOVO NORDISK A/S (DK) | 2002-07-09 | — | — | US | disclosed |
| EP-1147092-A1 | SUBSTITUTED IMIDAZOLES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000042023-A1 | SUBSTITUTED IMIDAZOLES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2000-07-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130345192-A1 | HETEROCYCLIC TYROSINE KINASE INHIBITORS | TEC, ABL1, LCK | TSHR 3511/4885IDO1 1537/4885TACR1 4423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.