SCHEMBL459297

SCHEMBL459297

Cc1cc(CN=C=O)cc(CN=C=O)c1

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PGK1 P00558 1/20 0.40
PGK2 P07205 1/20 0.40
CYP3A4 P08684 1/20 0.32
GRIN2B Q13224 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27705400 0.95 PGK1 (0.35) PGK1PGK2CYP3A4GRIN2B
SCHEMBL199862 0.90 CYP3A4 (0.32) CYP3A4
SCHEMBL11162063 0.84 RXRA (0.33) CYP3A4
SCHEMBL27545979 0.84 RXRA (0.33) CYP3A4
SCHEMBL17049997 0.79 MIF (0.50) PGK1PGK2CYP3A4GRIN2B
SCHEMBL21175624 0.79 CYP3A4 (0.31) CYP3A4
SCHEMBL436041 0.79 CYP3A4 (0.31) CYP3A4
SCHEMBL15435871 0.79 MIF (0.41)
SCHEMBL31158081 0.79 TAAR1 (0.47)
SCHEMBL1023733 0.79 TAAR1 (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116533420-A Preparation method of near infrared barrier polyurethane lens 浙江伟星光学股份有限公司 2023-08-04 CN claimed
EP-4731688-A1 METHOD FOR THE PRODUCTION OF A HYDROXYL-GROUP TERMINATED OXAZOLIDINONE COMPOSITION Covestro Deutschland AG (DE) 2026-04-29 EP disclosed
US-20260071091-A1 SELF-HEALING TRANSPARENT COATING COMPOSITION USING SUNLIGHT AND APPLICATION THEREOF KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2026-03-12 US disclosed
US-12559586-B2 Compositions containing uretdione groups crosslinking at low temperatures COVESTRO DEUTSCHLAND AG (DE) 2026-02-24 US disclosed
EP-4688893-A1 EPOXY-GROUP TERMINATED AND ISOCYANURATE-GROUP CONTAINING POLYOXAZOLIDINONES AND THEIR USE IN COATING COMPOSITIONS Covestro Deutschland AG (DE) 2026-02-11 EP disclosed
WO-2025224211-A1 SINGLE-COMPONENT SYSTEM FOR COATINGS COVESTRO DEUTSCHLAND AG (DE) 2025-10-30 WO disclosed
WO-2025224257-A1 SINGLE-COMPONENT COATING MATERIAL FOR FOOD CONTAINERS COVESTRO DEUTSCHLAND AG (DE) 2025-10-30 WO disclosed
EP-4640731-A1 ONE-COMPONENT COATING COMPOSITION FOR FOOD CONTAINERS Covestro Deutschland AG (DE) 2025-10-29 EP disclosed
EP-4640732-A1 ONE-COMPONENT SYSTEM FOR COATINGS Covestro Deutschland AG (DE) 2025-10-29 EP disclosed
EP-4357382-B1 IONICALLY MODIFIED POLYISOCYANATE MIXTURE COVESTRO DEUTSCHLAND AG (DE) 2025-07-23 EP disclosed
US-20130158145-A1 POLYURETHANE HAVING HIGH LIGHT REFRACTION BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-06-20 US disclosed
US-20130158146-A1 POLYISOCYANATE MIXTURES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-06-20 US disclosed
EP-2596040-A1 POLYURETHANE HAVING LOW VOLUME SHRINKAGE Bayer Intellectual Property GmbH (DE) 2013-05-29 EP disclosed
EP-2596042-A1 POLYISOCYANATE MIXTURES Bayer Intellectual Property GmbH (DE) 2013-05-29 EP disclosed
EP-2596041-A1 POLYURETHANE HAVING HIGH LIGHT REFRACTION Bayer Intellectual Property GmbH (DE) 2013-05-29 EP disclosed
US-20130116357-A1 POLYURETHANE HAVING LOW VOLUME SHRINKAGE BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-05-09 US disclosed
WO-2012010526-A1 POLYURETHANE HAVING HIGH LIGHT REFRACTION BAYER MATERIALSCIENCE AG (DE) 2012-01-26 WO disclosed
WO-2012010523-A1 POLYISOCYANATE MIXTURES BAYER MATERIALSCIENCE AG (DE) 2012-01-26 WO disclosed
WO-2012010524-A1 POLYURETHANE HAVING LOW VOLUME SHRINKAGE BAYER MATERIALSCIENCE AG (DE) 2012-01-26 WO disclosed
US-4408034-A HIGH SPEED, TERTIARY AMINE, VAPOR PHASE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1983-10-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559586-B2 Compositions containing uretdione groups crosslinking at low temperatures URB2, UQCRB, UQCRC2 PGK1 1578/4885PGK2 792/4885CYP3A4 1937/4885
US-20260071091-A1 SELF-HEALING TRANSPARENT COATING COMPOSITION USING SUNLIGHT AND APPLICATION THEREOF PCNA, CUTA, COL1A1 PGK1 2896/4885PGK2 3961/4885CYP3A4 1830/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.