Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromobenzene SCHEMBL28192537 | 0.84 | HPGD (0.46) | HPGDPOLBALDH1A1KDM4ETDP1 | |
| Biphenyl SCHEMBL11806686 | 0.83 | SMN1; SMN2 (0.53) | HPGDPOLBALDH1A1KDM4EMAPT | |
| Benzene SCHEMBL27929884 | 0.82 | TSHR (0.50) | POLBALDH1A1KDM4EMAPTGAA | |
| Bromobenzene SCHEMBL28295090 | 0.82 | HPGD (0.45) | HPGDPOLBALDH1A1KDM4ETDP1 | |
| Bromobenzene SCHEMBL27322327 | 0.82 | KMT2A (0.45) | HPGDPOLBALDH1A1KDM4ETDP1 | |
| Toluene SCHEMBL27324786 | 0.82 | POLB (0.47) | POLBALDH1A1KDM4ETDP1GAA | |
| Phenol SCHEMBL7218267 | 0.82 | ESRRB (0.50) | HPGDPOLBALDH1A1KDM4ETDP1 | |
| Bromobenzene SCHEMBL28154889 | 0.81 | ALDH1A1 (0.55) | HPGDALDH1A1KDM4EMAPTTDP1 | |
| Aniline SCHEMBL28348599 | 0.80 | POLB (0.46) | POLBALDH1A1KDM4EGAAELANE | |
| Phenol SCHEMBL27776505 | 0.80 | ESRRB (0.49) | HPGDPOLBALDH1A1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1028529-C | Process for preparing endophenylene oxabicycloheptyl substituted prostaglandin analogs | SQUIBB & SONS INC (US) | 1995-05-24 | — | — | CN | disclosed |
| CN-1046163-A | The heterocycleamide prostanoid analogue that is used for the treatment of the interior phenylene 7-oxabicyclo heptyl replacement of thrombosis and vasospasm disease | SQUIBB & SONS INC (US) | 1990-10-17 | — | — | CN | disclosed |