Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromobenzene SCHEMBL27324784 | 0.84 | HPGD (0.46) | HPGDPOLBALDH1A1KDM4ESLC6A3 | |
| Biphenyl SCHEMBL27695862 | 0.83 | POLB (0.48) | HPGDPOLBALDH1A1KDM4ELMNA | |
| Benzene SCHEMBL28075751 | 0.82 | TSHR (0.50) | POLBALDH1A1KDM4ELMNACYP4F2 | |
| Bromobenzene SCHEMBL28295090 | 0.82 | HPGD (0.45) | HPGDPOLBALDH1A1KDM4ESLC6A3 | |
| Bromobenzene SCHEMBL27322327 | 0.82 | KMT2A (0.45) | HPGDPOLBALDH1A1KDM4ESLC6A3 | |
| Fluorobenzene SCHEMBL27719427 | 0.80 | SLC6A4 (0.46) | POLBALDH1A1KDM4ESLC6A3LMNA | |
| Chlorobenzene SCHEMBL7570717 | 0.80 | KLK7 (0.47) | POLBALDH1A1KDM4ESLC6A3LMNA | |
| Bromobenzene SCHEMBL27304905 | 0.79 | ALDH1A1 (0.52) | HPGDALDH1A1KDM4ESLC6A3LMNA | |
| SCHEMBL21453 | 0.75 | — | — | |
| SCHEMBL28412102 | 0.75 | TSHR (0.59) | ALDH1A1KDM4ELMNACYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107522634-A | Biaryl ureas carboxylic acid derivates or its salt and its production and use | 复旦大学 | 2017-12-29 | — | — | CN | disclosed |