Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL28295092 | 0.90 | KMT2A (0.39) | HPGDPOLBALDH1A1KMT2AMEN1 | |
| Biphenyl SCHEMBL3991647 | 0.84 | POLB (0.47) | HPGDPOLBALDH1A1KMT2AMEN1 | |
| Phenol SCHEMBL27480309 | 0.82 | ESRRB (0.49) | HPGDPOLBALDH1A1TDP1TSHR | |
| Toluene SCHEMBL27945492 | 0.82 | POLB (0.46) | POLBALDH1A1TDP1KMT2AMEN1 | |
| Bromobenzene SCHEMBL28192537 | 0.82 | HPGD (0.46) | HPGDPOLBALDH1A1TDP1KMT2A | |
| Bromobenzene SCHEMBL27324784 | 0.82 | HPGD (0.46) | HPGDPOLBALDH1A1TDP1KMT2A | |
| Benzene SCHEMBL28161453 | 0.81 | LMNA (0.54) | POLBALDH1A1KMT2AMEN1TSHR | |
| Phenol SCHEMBL28008035 | 0.81 | ESRRB (0.47) | HPGDPOLBALDH1A1TDP1TSHR | |
| Benzophenone SCHEMBL7081803 | 0.81 | ALDH1A1 (0.54) | HPGDPOLBALDH1A1TDP1L3MBTL1 | |
| Bromobenzene SCHEMBL27322327 | 0.81 | KMT2A (0.45) | HPGDPOLBALDH1A1TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109734617-A | A kind of method for splitting replacing aromatic ring phenylglycine aliphatic alcohol ester | 华东理工大学 | 2019-05-10 | — | — | CN | disclosed |