SCHEMBL27324933

SCHEMBL27324933

CC(C)(C)c1cccc(C(=O)O)c1C(C)(C)C.[Ni]

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.46
CA2 P00918 3/20 0.43
ALDH1A1 P00352 4/20 0.43
KDM4E B2RXH2 2/20 0.41
HPGD P15428 2/20 0.41
HSD17B10 Q99714 2/20 0.41
TAS2R14 Q9NYV8 1/20 0.40
NOTUM Q6P988 1/20 0.39
TSHR P16473 2/20 0.38
NR4A1 P22736 1/20 0.38
NR4A2 P43354 1/20 0.38
NR4A3 Q92570 1/20 0.38
GABRA1 P14867 1/20 0.38
GABRB2 P47870 1/20 0.38
CA1 P00915 2/20 0.38
MMP2 P08253 2/20 0.38
MMP1 P03956 1/20 0.38
MMP9 P14780 1/20 0.38
MMP8 P22894 1/20 0.38
MMP13 P45452 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29678146 0.98 ALOX15 (0.47) ALOX15CA2ALDH1A1KDM4EHPGD
SCHEMBL273494 0.98 ALOX15 (0.47) ALOX15CA2ALDH1A1KDM4EHPGD
SCHEMBL27764801 0.96 ALOX15 (0.46) ALOX15CA2ALDH1A1KDM4EHPGD
Ethylene Glycol SCHEMBL28603660 0.91 ALOX15 (0.42) ALOX15CA2ALDH1A1KDM4EHPGD
SCHEMBL8878932 0.87 ALOX15 (0.44) ALOX15CA2ALDH1A1KDM4EHPGD
SCHEMBL161622 0.86 ALOX15 (0.53) ALOX15CA2ALDH1A1KDM4EHPGD
Propylene Glycol SCHEMBL28918055 0.85 ALOX15 (0.38) ALOX15CA2ALDH1A1KDM4EHPGD
SCHEMBL29263958 0.84 CA2 (0.46) ALOX15CA2ALDH1A1TSHRGABRA1
SCHEMBL28064460 0.84 ALOX15 (0.52) ALOX15CA2ALDH1A1KDM4EHPGD
SCHEMBL1434698 0.82 CA2 (0.45) ALOX15CA2ALDH1A1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106414529-B Polyalkenyl coupling agent and conjugated diolefin polymer prepared therefrom 科腾聚合物美国有限责任公司 2019-05-10 CN disclosed
CN-106414529-A Polyalkenyl coupling agent and conjugated diene polymers prepared therefrom 科腾聚合物美国有限责任公司 2017-02-15 CN disclosed
CN-103173264-A Marine engine lubrication INFINEUM INT LTD 2013-06-26 CN disclosed
CN-1576359-B Viscosity index improvers for lubricating oil compositions INFINEUM INT LTD 2010-07-28 CN disclosed
CN-101161799-A Lubricating oil compositions INFINEUM INT LTD (GB) 2008-04-16 CN disclosed
CN-1576359-A Viscosity index improvers for lubricating oil compositions INFINEUM INT LTD (GB) 2005-02-09 CN disclosed
CN-1029007-C Lubricating oil composition and functionalised polymers therefor SHELL INTERNATIONALE RESEARCHJ (NL) 1995-06-21 CN disclosed
CN-1042563-A Lubricating oil composition and used functionalised polymers thereof SHELL INT RESEARCH (NL) 1990-05-30 CN disclosed