SCHEMBL1434698

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29263958	0.86	CA2 (0.46)	CA2GABRA1GABRB2ALDH1A1TSHR
	SCHEMBL273494	0.84	ALOX15 (0.47)	CA2GABRA1GABRB2ALDH1A1TSHR
	SCHEMBL29678146	0.84	ALOX15 (0.47)	CA2GABRA1GABRB2ALDH1A1TSHR
	SCHEMBL373525	0.83	CA2 (0.48)	CA2GABRA1GABRB2ALDH1A1TSHR
	SCHEMBL28774188	0.82	CA2 (0.43)	CA2GABRA1GABRB2ALDH1A1TSHR
	SCHEMBL30706305	0.82	CA2 (0.43)	CA2GABRA1GABRB2ALDH1A1TSHR
	SCHEMBL28819980	0.82	CA2 (0.43)	CA2GABRA1GABRB2ALDH1A1TSHR
	SCHEMBL27324933	0.82	ALOX15 (0.46)	CA2GABRA1GABRB2ALDH1A1TSHR
	SCHEMBL27764801	0.82	ALOX15 (0.46)	CA2GABRA1GABRB2ALDH1A1TSHR
	SCHEMBL8055375	0.82	CA2 (0.43)	CA2GABRA1GABRB2ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.