Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | IDE | P14735 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31532599 | 0.78 | ALDH1A1 (0.33) | ALDH1A1TSHRNPSR1L3MBTL1LMNA | |
| SCHEMBL9932677 | 0.72 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1MEN1KMT2AIDE | |
| SCHEMBL16302786 | 0.72 | ALDH1A1 (0.69) | ALDH1A1NPSR1MEN1KMT2AMAPT | |
| SCHEMBL323788 | 0.70 | CYP1A2 (0.50) | ALDH1A1NPSR1L3MBTL1MEN1KMT2A | |
| SCHEMBL31532493 | 0.70 | FAAH (0.37) | ALDH1A1NPSR1L3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL327504 | 0.69 | CYP1A2 (0.49) | ALDH1A1NPSR1L3MBTL1MEN1KMT2A | |
| SCHEMBL9963099 | 0.69 | ALDH1A1 (0.68) | ALDH1A1NPSR1L3MBTL1MEN1KMT2A | |
| SCHEMBL27324615 | 0.69 | SIGMAR1 (0.39) | ALDH1A1MEN1KMT2ALMNASIGMAR1 | |
| Trifluoroacetic Acid SCHEMBL1514776 | 0.68 | ALDH1A1 (0.53) | ALDH1A1NPSR1MEN1KMT2AGAA | |
| SCHEMBL2102695 | 0.68 | POLB (0.38) | ALDH1A1MEN1KMT2ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024088922-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF MONOACYLGLYCEROL LIPASE (MAGL) | F. HOFFMANN-LA ROCHE AG (CH) | 2024-05-02 | — | — | WO | disclosed |