Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | CMA1 | P23946 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GSK3A | P49840 | 2/20 | 0.49 |
| ▸ | GSK3B | P49841 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20133743 | 0.86 | GAA (0.57) | GAACMA1MEN1KMT2AALDH1A1 | |
| SCHEMBL18076484 | 0.82 | GAA (0.53) | GAACMA1MEN1KMT2AALDH1A1 | |
| SCHEMBL18089240 | 0.79 | MMP1 (0.49) | GAACMA1MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL18076555 | 0.78 | MMP1 (0.48) | GAACMA1MEN1KMT2AALDH1A1 | |
| SCHEMBL1448471 | 0.78 | GSK3A (0.51) | GAACMA1MEN1KMT2APOLB | |
| SCHEMBL17360667 | 0.78 | CMA1 (0.59) | GAACMA1MEN1KMT2AALDH1A1 | |
| SCHEMBL11432095 | 0.76 | GAA (0.68) | GAACMA1MEN1KMT2AALDH1A1 | |
| SCHEMBL4003120 | 0.74 | GAA (0.66) | GAACMA1MEN1KMT2AALDH1A1 | |
| SCHEMBL3459387 | 0.73 | L3MBTL1 (0.64) | GAACMA1MEN1KMT2AALDH1A1 | |
| SCHEMBL6407514 | 0.73 | MEN1 (0.64) | GAACMA1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023235384-A1 | COMPOUNDS FOR ENHANCING READ THROUGH OF GENES CONTAINING PREMATURE TERMINATION CODONS AND METHODS FOR MAKING AND USING THE SAME | SANOFI US SERVICES INC. (US) | 2023-12-07 | — | — | WO | disclosed |