Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5142042 | 1.00 | LMNA (0.56) | LMNAALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL11331822 | 1.00 | LMNA (0.56) | LMNAALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL27304612 | 1.00 | LMNA (0.56) | LMNAALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL3438481 | 1.00 | LMNA (0.56) | LMNAALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL4557001 | 1.00 | LMNA (0.56) | LMNAALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL9033403 | 1.00 | LMNA (0.56) | LMNAALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL648992 | 1.00 | LMNA (0.56) | LMNAALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL9208146 | 1.00 | LMNA (0.56) | LMNAALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL3632571 | 0.97 | ALDH1A1 (0.52) | LMNAALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL10422652 | 0.94 | LMNA (0.62) | LMNAALDH1A1TDP1TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1035381-C | Radicicol derivatives, their preparation and their anti-tumor activity | SANKYO CO (JP) | 1997-07-09 | — | — | CN | disclosed |
| CN-1059720-A | Radicicol derivatives, its preparation method and anti-tumor activity thereof | SANKYO CO (JP) | 1992-03-25 | — | — | CN | disclosed |