Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL774942 | 0.98 | TDP1 (0.39) | ALDH1A1KMT2AMEN1MAPTTDP1 | |
| SCHEMBL28992516 | 0.81 | LMNA (0.38) | ALDH1A1KMT2AMEN1MAPTTDP1 | |
| Cyclopentane SCHEMBL29109135 | 0.80 | MCL1 (0.42) | ALDH1A1KMT2AMEN1MAPTTDP1 | |
| SCHEMBL7807159 | 0.76 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1TDP1CES2 | |
| SCHEMBL774943 | 0.76 | ALDH1A1 (0.35) | ALDH1A1KMT2AMEN1MAPTTDP1 | |
| SCHEMBL4934011 | 0.76 | SMN1; SMN2 (0.40) | ALDH1A1KMT2AMEN1TDP1POLB | |
| SCHEMBL11862575 | 0.75 | CES2 (0.55) | ALDH1A1KMT2ATDP1POLBCES2 | |
| SCHEMBL248821 | 0.75 | CES2 (0.55) | ALDH1A1KMT2ATDP1POLBCES2 | |
| SCHEMBL776566 | 0.75 | CES2 (0.55) | ALDH1A1KMT2ATDP1POLBCES2 | |
| SCHEMBL6939791 | 0.75 | CES2 (0.55) | ALDH1A1KMT2ATDP1POLBCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1034716-A | Disubstituted pyridines and preparation method thereof | BAYER AG (DE) | 1989-08-16 | — | — | CN | disclosed |