Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10401135 | 0.86 | HSD17B10 (0.37) | ALDH1A1MAPTNPC1MEN1KMT2A | |
| SCHEMBL8329867 | 0.86 | HSD17B10 (0.37) | ALDH1A1MAPTNPC1MEN1KMT2A | |
| SCHEMBL5298283 | 0.85 | ALDH1A1 (0.36) | ALDH1A1MAPTNPC1MEN1KMT2A | |
| SCHEMBL9055334 | 0.85 | ALDH1A1 (0.36) | ALDH1A1MAPTNPC1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL27328374 | 0.84 | ALDH1A1 (0.38) | ALDH1A1MAPTNPC1MEN1KMT2A | |
| SCHEMBL27622470 | 0.80 | GABRA5 (0.40) | ALDH1A1MAPTNPC1MEN1KMT2A | |
| SCHEMBL1000856 | 0.76 | ALDH1A1 (0.44) | ALDH1A1MAPTNPC1MEN1KMT2A | |
| SCHEMBL7106196 | 0.76 | ALDH1A1 (0.42) | ALDH1A1MAPTNPC1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11102564 | 0.75 | ALDH1A1 (0.46) | ALDH1A1MAPTNPC1MEN1KMT2A | |
| SCHEMBL1417466 | 0.74 | GABRA5 (0.47) | ALDH1A1MAPTNPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1059438-C | Method for preparing cynnematin antibiotic | BRISTOL MYERS SQUIBB CO (US) | 2000-12-13 | — | — | CN | disclosed |
| CN-1036587-C | Process for preparing cephalosporin antibiotics | BRISTOL MYERS SQUIBB CO (US) | 1997-12-03 | — | — | CN | disclosed |
| CN-1158333-A | Method for preparing cynnematin antibiotic | BRISTOL MYERS SQUIBB CO (US) | 1997-09-03 | — | — | CN | disclosed |