Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NOS1 | P29475 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.36 |
| ▸ | ATP4A | P20648 | 1/20 | 0.36 |
| ▸ | ATP4B | P51164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11102564 | 0.98 | ALDH1A1 (0.46) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL27851070 | 0.82 | GABRA5 (0.43) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL1417466 | 0.82 | GABRA5 (0.47) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL27336449 | 0.80 | ALDH1A1 (0.47) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL6216370 | 0.79 | ALDH1A1 (0.50) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL2771532 | 0.78 | RAB9A (0.38) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL27770260 | 0.78 | HDAC3 (0.37) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL11668532 | 0.78 | ALDH1A1 (0.45) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL27622470 | 0.78 | GABRA5 (0.40) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL7380565 | 0.78 | ALDH1A1 (0.45) | ALDH1A1MAPTMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109438385-A | The preparation method of high-purity 2- amino -4- thiazolyl acetic acid | 山东金城医药化工有限公司 | 2019-03-08 | — | — | CN | claimed |
| CN-105968069-B | A kind of synthetic method of cefotiam hexetil process contaminants | 浙江永宁药业股份有限公司 | 2018-10-16 | — | — | CN | claimed |
| CN-106908597-A | A kind of preparation method of immune affinity column | 花锦 | 2017-06-30 | — | — | CN | claimed |
| CN-106268702-A | A kind of based on the method for mercury ion in thiazole functionalization superfine fibre fast selective absorption water | 天津工业大学 | 2017-01-04 | — | — | CN | claimed |
| CN-104311548-B | Cadmium ion sensor and functional polyurathamc | 苏州太湖电工新材料股份有限公司 | 2016-11-16 | — | — | CN | claimed |
| CN-105968069-A | Synthesis method of cefotiam hexetil process impurity | 浙江永宁药业股份有限公司 | 2016-09-28 | — | — | CN | claimed |
| CN-105439977-A | Preparation methods for acotiamide and hydrochloride thereof | GUANGZHOU REGENEX CORP | 2016-03-30 | — | — | CN | claimed |
| CN-105198832-A | Preparation method of acotiamide hydrochloride | SHANDONG FUCHUANG PHARMACEUTICAL TECHNOLOGY CO LTD | 2015-12-30 | — | — | CN | claimed |
| CN-104045606-B | One kettle way prepares the method for Ah examining for amine hydrochlorate | Hangzhou Xin Bosi biological medicine company limited (CN) | 2015-09-30 | — | — | CN | claimed |
| CN-104672163-A | Method for preparing hydrochloric acid acotiamide | SHANDONG FUCHUANG PHARMACEUTICAL CO LTD | 2015-06-03 | — | — | CN | claimed |
| CN-104524999-A | Panel type modified polyvinylidene fluoride ultrafiltration membrane and preparation method thereof | UNIV JINAN | 2015-04-22 | — | — | CN | claimed |
| CN-104311548-A | Cadmium ion sensor and functional foamed polyurethane | SUZHOU TAIHU ELECTRIC NEW MATERIAL CO LTD | 2015-01-28 | — | — | CN | claimed |
| CN-104230840-A | Synthesis method of mirabegron | ANHUI LIANCHUANG PHARMACEUTICAL CHEMISTRY CO LTD | 2014-12-24 | — | — | CN | claimed |
| CN-104045606-A | One-pot method for preparing acotiamide hydrochloride | HANGZHOU SIMBOS PHARM CO LTD | 2014-09-17 | — | — | CN | claimed |
| CN-103387500-A | Preparation methods for mirabegron and intermediate thereof | SHANGHAI INST PHARM INDUSTRY | 2013-11-13 | — | — | CN | claimed |
| CN-102070553-B | Synthesis method of thiazole-4-formaldehyde | XIAN RUILIAN MODERN ELECTRONIC CHEMICALS CO LTD | 2013-08-07 | — | — | CN | claimed |
| CN-102731431-A | Preparation method of 5-bromothiazole-4-formic acid | CGENE TECH SUZHOU CHINA CO LTD | 2012-10-17 | — | — | CN | claimed |
| CN-102070553-A | Synthesis method of thiazole-4-formaldehyde | XIAN RUILIAN MODERN ELECTRONIC CHEMICALS CO LTD | 2011-05-25 | — | — | CN | claimed |
| CN-101362735-A | Preparation method of ethyl 2-[[(bezyloxy)carbonyl]amido]-4-thiazolyl acetate | SHANDONG JINCHENG PHARMACEUTIC (CN) | 2009-02-11 | — | — | CN | claimed |
| CN-101182314-A | Method for preparing 2-(2-butoxy carbonyl amino thiazole-4-group)-2-pentenoic acid ester | SHANDONG JINCHENG PHARMACEUTIC (CN) | 2008-05-21 | — | — | CN | claimed |