Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CES2 | O00748 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.50 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | SOX18 | P35713 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5969148 | 0.85 | ESRRG (0.60) | CYP1A2GAAHDAC1HDAC8PDPK1 | |
| SCHEMBL761158 | 0.85 | KDM4E (0.61) | CYP1A2CES2MAPTHTTKDM4E | |
| SCHEMBL6198665 | 0.85 | CES2 (0.54) | CYP1A2CES2MAPTHTTKDM4E | |
| SCHEMBL9002952 | 0.84 | HPGD (0.65) | CYP1A2MAPTHTTKDM4EALDH1A1 | |
| SCHEMBL1984009 | 0.83 | MAPT (0.56) | CYP1A2CES2MAPTHTTKDM4E | |
| SCHEMBL4857939 | 0.83 | MAPT (0.56) | CYP1A2CES2MAPTHTTKDM4E | |
| SCHEMBL1695082 | 0.82 | NR1H4 (0.58) | CYP1A2HDAC1HDAC8FFAR1NR1H4 | |
| SCHEMBL3240006 | 0.82 | CES2 (0.66) | CYP1A2CES2MAPTHTTKDM4E | |
| SCHEMBL13652571 | 0.82 | MTNR1A (0.62) | CES2MAPTHTTKDM4EALDH1A1 | |
| SCHEMBL31713941 | 0.82 | NR1H4 (0.57) | MAPTHTTKDM4EGAANR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250188110-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2025-06-12 | — | — | US | disclosed |
| US-20250064989-A1 | COMPOSITION AND METHODS FOR TUMOR IMAGING AND TREATMENT | THE UNIVERSITY OF CHICAGO (US) | 2025-02-27 | — | — | US | disclosed |
| US-12138320-B2 | Composition and methods for tumor imaging and treatment | THE UNIVERSITY OF CHICAGO (US) | 2024-11-12 | — | — | US | disclosed |
| US-9249128-B2 | Anti-cancer serine hydrolase inhibitory carbamates | THE SCRIPPS RESEARCH INSTITUTE (US) | 2016-02-02 | — | — | US | disclosed |
| US-20130281453-A1 | ANTI-CANCER SERINE HYDROLASE INHIBITORY CARBAMATES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2013-10-24 | — | — | US | disclosed |
| EP-2632912-A2 | ANTI-CANCER SERINE HYDROLASE INHIBITORY CARBAMATES | The Scripps Research Institute (US) | 2013-09-04 | — | — | EP | disclosed |
| WO-2012058115-A2 | ANTI-CANCER SERINE HYDROLASE INHIBITORY CARBAMATES | CRAVATT BENJAMIN (US) | 2012-05-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250064989-A1 | COMPOSITION AND METHODS FOR TUMOR IMAGING AND TREATMENT | NCEH1, CES1, ASAH1 | CYP1A2 3352/4885CES2 149/4885MAPT 3562/4885 |
| US-20250188110-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | KMT5A, KMT5B, KMT5C | CYP1A2 835/4885CES2 2259/4885MAPT 1942/4885 |
| US-20130281453-A1 | ANTI-CANCER SERINE HYDROLASE INHIBITORY CARBAMATES | AADAC, DDAH1, PRSS1 | CYP1A2 4014/4885CES2 679/4885MAPT 4221/4885 |
| US-12138320-B2 | Composition and methods for tumor imaging and treatment | NCEH1, CES1, ASAH1 | CYP1A2 3352/4885CES2 149/4885MAPT 3562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.