SCHEMBL27328484

SCHEMBL27328484

CCCCCCCCCCCCCC(CC(CCc1ccc(C=O)c(OC)c1)OC)OC

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 5/20 0.48
LTA4H P09960 4/20 0.44
CYP3A4 P08684 5/20 0.43
CYP2C8 P10632 4/20 0.43
CYP2C9 P11712 4/20 0.43
CYP2B6 P20813 4/20 0.43
CYP2C19 P33261 4/20 0.43
CYP1A2 P05177 3/20 0.43
CYP2D6 P10635 2/20 0.43
CYP2A6 P11509 2/20 0.43
CYP2E1 P05181 1/20 0.43
PPARG P37231 1/20 0.43
PPARA Q07869 1/20 0.43
TRPV1 Q8NER1 1/20 0.41
ALDH1A1 P00352 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
STAT3 P40763 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31455929 0.82 PPARG (0.59) HTR1ALTA4HCYP3A4CYP2C8CYP2C9
SCHEMBL31442610 0.82 PPARG (0.59) HTR1ALTA4HCYP3A4CYP2C8CYP2C9
SCHEMBL27002142 0.81 PPARG (0.57) HTR1ALTA4HCYP3A4CYP2C8CYP2C9
SCHEMBL31455942 0.79 ALDH1A1 (0.53) HTR1ALTA4HCYP3A4CYP2C8CYP2C9
SCHEMBL465084 0.77 ALDH1A1 (0.56) CYP3A4PPARGPPARAALDH1A1L3MBTL1
SCHEMBL30515451 0.73 LTA4H (0.67) HTR1ALTA4HCYP3A4CYP2C8CYP2C9
SCHEMBL23370854 0.73 HTR1A (0.64) HTR1ALTA4HCYP3A4CYP2C8CYP2C9
SCHEMBL23370864 0.73 HTR1A (0.64) HTR1ALTA4HCYP3A4CYP2C8CYP2C9
SCHEMBL23370862 0.73 HTR1A (0.64) HTR1ALTA4HCYP3A4CYP2C8CYP2C9
SCHEMBL23370853 0.73 HTR1A (0.64) HTR1ALTA4HCYP3A4CYP2C8CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1041920-C Glycerin derivative and its pharmacological use EISAI CO LTD (JP) 1999-02-03 CN disclosed
CN-1039414-A Glycerol derivatives and pharmaceutical use thereof EISAI CO LTD (JP) 1990-02-07 CN disclosed