Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | THRA | P10827 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NAAA | Q02083 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20198772 | 0.94 | THRA (0.48) | DNM1MAPTEPHX2THRATHRB | |
| SCHEMBL22767923 | 0.93 | DNM1 (0.47) | DGKADNM1MAPTEPHX2THRA | |
| SCHEMBL31245951 | 0.89 | DNM1 (0.52) | DGKADNM1MAPTEPHX2THRA | |
| SCHEMBL31245954 | 0.89 | DNM1 (0.52) | DGKADNM1MAPTEPHX2THRA | |
| SCHEMBL31245863 | 0.88 | DNM1 (0.51) | DGKADNM1MAPTEPHX2THRA | |
| SCHEMBL22391191 | 0.83 | SMN1; SMN2 (0.57) | THRATHRBSMN1; SMN2NAAAL3MBTL1 | |
| SCHEMBL22767782 | 0.82 | EPHX2 (0.47) | MAPTEPHX2ALDH1A1HPGD | |
| SCHEMBL22767943 | 0.82 | EPHX2 (0.47) | MAPTEPHX2ALDH1A1HPGD | |
| SCHEMBL22767933 | 0.82 | FAAH (0.45) | MAPTEPHX2THRATHRBSMN1; SMN2 | |
| SCHEMBL31245975 | 0.81 | THRA (0.42) | DNM1MAPTEPHX2THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024119098-A1 | LIPID NANOPARTICLE (LNP) DELIVERY SYSTEMS AND FORMULATIONS | PRIME MEDICINE, INC. (US) | 2024-06-06 | — | — | WO | disclosed |