SCHEMBL2732933

SCHEMBL2732933

CC(=Cc1ccc(-c2ccc(C=C(C)C(=O)O)cc2)cc1)C(=O)O

nearest known ligand 0.72

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.72
TP53 P04637 1/20 0.55
TBXAS1 P24557 5/20 0.47
PTGS2 P35354 1/20 0.46
HTT P42858 1/20 0.44
POLB P06746 2/20 0.44
ALDH1A1 P00352 2/20 0.44
ESR1 P03372 1/20 0.44
GLA P06280 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
KDM4E B2RXH2 1/20 0.42
APEX1 P27695 2/20 0.41
RXRA P19793 1/20 0.40
RXRB P28702 1/20 0.40
NR4A2 P43354 1/20 0.40
RXRG P48443 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3414243 1.00 AKR1C3 (0.72) AKR1C3TP53TBXAS1PTGS2HTT
SCHEMBL532625 0.94 AKR1C3 (0.77) AKR1C3TP53TBXAS1HTTPOLB
SCHEMBL532624 0.94 AKR1C3 (0.77) AKR1C3TP53TBXAS1HTTPOLB
SCHEMBL2462984 0.93 AKR1C3 (0.82) AKR1C3TP53TBXAS1HTTPOLB
SCHEMBL2462983 0.93 AKR1C3 (0.82) AKR1C3TP53TBXAS1HTTPOLB
SCHEMBL4806412 0.92 AKR1C3 (0.62) AKR1C3TP53TBXAS1PTGS2HTT
SCHEMBL4805932 0.92 AKR1C3 (0.62) AKR1C3TP53TBXAS1PTGS2HTT
SCHEMBL4808963 0.90 AKR1C3 (0.60) AKR1C3TP53TBXAS1HTTALDH1A1
SCHEMBL4801214 0.90 AKR1C3 (0.60) AKR1C3TP53TBXAS1PTGS2POLB
SCHEMBL1842887 0.90 AKR1C3 (0.60) AKR1C3TP53PTGS2HTTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110300919-B Liquid crystal display device having a plurality of pixel electrodes DIC株式会社 2022-07-01 CN disclosed
EP-3257916-B1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2021-11-17 EP disclosed
US-20210277310-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2021-09-09 US disclosed
CN-105814480-B Liquid crystal display device having a plurality of pixel electrodes DIC株式会社 2020-01-07 CN disclosed
US-20190113792-A1 LIQUID CRYSTAL PANEL AND METHOD FOR MANUFACTURING LIQUID CRYSTAL PANEL SHARP KABUSHIKI KAISHA (JP) 2019-04-18 US disclosed
US-20180119010-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2018-05-03 US disclosed
US-9864236-B2 Method for manufacturing liquid crystal display device SHARP KABUSHIKI KAISHA (JP) 2018-01-09 US disclosed
EP-3260518-A1 LIQUID CRYSTALLINE MEDIUM Merck Patent GmbH (DE) 2017-12-27 EP disclosed
EP-3257916-A1 LIQUID CRYSTALLINE MEDIUM Merck Patent GmbH (DE) 2017-12-20 EP disclosed
US-9817274-B2 Method for manufacturing liquid crystal display device SHARP KABUSHIKI KAISHA (JP) 2017-11-14 US disclosed
US-20110255048-A1 LIQUID-CRYSTAL DISPLAY MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 2011-10-20 US disclosed
US-20100272925-A1 LIQUID-CRYSTAL DISPLAY MERCK PATENT GESELLSCHAFT (DE) 2010-10-28 US disclosed
EP-2243812-A2 Liquid crystal display Merck Patent GmbH (DE) 2010-10-27 EP disclosed
US-6982181-B2 Manufacturing process for ultra slim electrooptic display device unit SONY CORPORATION (JP) 2006-01-03 US disclosed
US-20050266591-A1 Manufacturing process for ultra slim electrooptic display device unit SONY CORPORATION 2005-12-01 US disclosed
US-6844905-B2 Alignment film, method for fabricating the alignment film, liquid crystal device, and projection type display device SEIKO EPSON CORPORATION (JP) 2005-01-18 US disclosed
US-20040259326-A1 Manufacturing process for ultra slim electrooptic display device unit SONY CORPORATION (JP) 2004-12-23 US disclosed
US-20040080685-A1 Alignment film, method for fabricating the alignment film, liquid crystal device, and projection type display device SEIKO EPSON CORPORATION (JP) 2004-04-29 US disclosed
WO-2001087829-A1 BISACYLGUANIDINE MERCK PATENT GMBH (DE) 2001-11-22 WO disclosed
US-4366171-A Fungicidal biphenyl esters, mixtures thereof and method of use GAF CORPORATION (US) 1982-12-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110255048-A1 LIQUID-CRYSTAL DISPLAY KLK3, BPHL, LPXN AKR1C3 3538/4885TP53 437/4885TBXAS1 3675/4885
US-20100272925-A1 LIQUID-CRYSTAL DISPLAY KLK3, BPHL, LPXN AKR1C3 2930/4885TP53 445/4885TBXAS1 3551/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.