SCHEMBL3414243

SCHEMBL3414243

C/C(=C\c1ccc(-c2ccc(/C=C(\C)C(=O)O)cc2)cc1)C(=O)O

nearest known ligand 0.72

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.72
TP53 P04637 1/20 0.55
TBXAS1 P24557 5/20 0.47
PTGS2 P35354 1/20 0.46
HTT P42858 1/20 0.44
POLB P06746 2/20 0.44
ALDH1A1 P00352 2/20 0.44
ESR1 P03372 1/20 0.44
GLA P06280 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
KDM4E B2RXH2 1/20 0.42
APEX1 P27695 2/20 0.41
RXRA P19793 1/20 0.40
RXRB P28702 1/20 0.40
NR4A2 P43354 1/20 0.40
RXRG P48443 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2732933 1.00 AKR1C3 (0.72) AKR1C3TP53TBXAS1PTGS2HTT
SCHEMBL532625 0.94 AKR1C3 (0.77) AKR1C3TP53TBXAS1HTTPOLB
SCHEMBL532624 0.94 AKR1C3 (0.77) AKR1C3TP53TBXAS1HTTPOLB
SCHEMBL2462984 0.93 AKR1C3 (0.82) AKR1C3TP53TBXAS1HTTPOLB
SCHEMBL2462983 0.93 AKR1C3 (0.82) AKR1C3TP53TBXAS1HTTPOLB
SCHEMBL4806412 0.92 AKR1C3 (0.62) AKR1C3TP53TBXAS1PTGS2HTT
SCHEMBL4805932 0.92 AKR1C3 (0.62) AKR1C3TP53TBXAS1PTGS2HTT
SCHEMBL4808963 0.90 AKR1C3 (0.60) AKR1C3TP53TBXAS1HTTALDH1A1
SCHEMBL4801214 0.90 AKR1C3 (0.60) AKR1C3TP53TBXAS1PTGS2POLB
SCHEMBL1842887 0.90 AKR1C3 (0.60) AKR1C3TP53PTGS2HTTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110300919-B Liquid crystal display device having a plurality of pixel electrodes DIC株式会社 2022-07-01 CN disclosed
EP-3257916-B1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2021-11-17 EP disclosed
CN-105814480-B Liquid crystal display device having a plurality of pixel electrodes DIC株式会社 2020-01-07 CN disclosed
EP-3260518-A1 LIQUID CRYSTALLINE MEDIUM Merck Patent GmbH (DE) 2017-12-27 EP disclosed
EP-3257916-A1 LIQUID CRYSTALLINE MEDIUM Merck Patent GmbH (DE) 2017-12-20 EP disclosed
US-9817274-B2 Method for manufacturing liquid crystal display device SHARP KABUSHIKI KAISHA (JP) 2017-11-14 US disclosed
EP-2691490-B1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2017-07-26 EP disclosed
EP-2243812-B2 Liquid crystal display MERCK PATENT GMBH (DE) 2016-09-07 EP disclosed
EP-2484743-B1 Liquid crystal display MERCK PATENT GMBH (DE) 2014-07-30 EP disclosed
EP-2691490-A1 LIQUID-CRYSTALLINE MEDIUM Merck Patent GmbH (DE) 2014-02-05 EP disclosed
EP-2484743-A2 Liquid crystal display Merck Patent GmbH (DE) 2012-08-08 EP disclosed
EP-2471892-A2 Liquid crystal display Merck Patent GmbH (DE) 2012-07-04 EP disclosed
EP-2243812-B1 Liquid crystal display MERCK PATENT GMBH (DE) 2012-06-13 EP disclosed
EP-2243812-A2 Liquid crystal display Merck Patent GmbH (DE) 2010-10-27 EP disclosed
US-6982181-B2 Manufacturing process for ultra slim electrooptic display device unit SONY CORPORATION (JP) 2006-01-03 US disclosed
US-20050266591-A1 Manufacturing process for ultra slim electrooptic display device unit SONY CORPORATION 2005-12-01 US disclosed
US-6844905-B2 Alignment film, method for fabricating the alignment film, liquid crystal device, and projection type display device SEIKO EPSON CORPORATION (JP) 2005-01-18 US disclosed
US-20040259326-A1 Manufacturing process for ultra slim electrooptic display device unit SONY CORPORATION (JP) 2004-12-23 US disclosed
US-20040080685-A1 Alignment film, method for fabricating the alignment film, liquid crystal device, and projection type display device SEIKO EPSON CORPORATION (JP) 2004-04-29 US disclosed
WO-2001087829-A1 BISACYLGUANIDINE MERCK PATENT GMBH (DE) 2001-11-22 WO disclosed