⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31752145 | 0.73 | ALDH1A1 (0.36) | — | |
| SCHEMBL27329638 | 0.69 | MAP4K4 (0.35) | — | |
| SCHEMBL9910062 | 0.69 | ALDH1A1 (0.30) | — | |
| SCHEMBL9299474 | 0.65 | NOTUM (0.39) | — | |
| SCHEMBL14147119 | 0.65 | — | — | |
| SCHEMBL7381477 | 0.63 | NPC1 (0.48) | — | |
| SCHEMBL22552381 | 0.62 | NOTUM (0.44) | — | |
| SCHEMBL29458555 | 0.62 | NOTUM (0.44) | — | |
| SCHEMBL22367279 | 0.60 | PDE10A (0.41) | — | |
| SCHEMBL21483642 | 0.59 | ALDH1A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023244806-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THAT DEGRADE SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A | Plexium, Inc. (US) | 2023-12-21 | — | — | WO | disclosed |