Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | CES2 | O00748 | 2/20 | 0.58 |
| ▸ | CES1 | P23141 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | SRC | P12931 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18869856 | 1.00 | LMNA (0.65) | LMNAMAPK1CES2CES1HPGD | |
| SCHEMBL4073357 | 1.00 | LMNA (0.65) | LMNAMAPK1CES2CES1HPGD | |
| Hydrochloric Acid SCHEMBL9617550 | 0.98 | LMNA (0.62) | LMNAMAPK1CES2CES1HPGD | |
| SCHEMBL28835827 | 0.98 | LMNA (0.62) | LMNAMAPK1CES2CES1HPGD | |
| Oxalic Acid SCHEMBL28129989 | 0.95 | LMNA (0.60) | LMNAMAPK1CES2CES1HPGD | |
| Acetaldehyde SCHEMBL11445863 | 0.89 | LMNA (0.54) | LMNAMAPK1CES2CES1HPGD | |
| SCHEMBL11877612 | 0.88 | LMNA (0.52) | LMNAMAPK1CES2CES1HPGD | |
| SCHEMBL8423523 | 0.81 | LMNA (0.60) | LMNAMAPK1CES2CES1HPGD | |
| Mandelic Acid SCHEMBL29777368 | 0.79 | LMNA (1.00) | LMNAMAPK1CES2CES1HPGD | |
| Mandelic Acid SCHEMBL255601 | 0.79 | LMNA (1.00) | LMNAMAPK1CES2CES1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106831821-B | 1/4 water Cefamandole nafate compounds | 海南灵康制药有限公司 | 2019-05-10 | — | — | CN | disclosed |
| CN-106699775-B | 1/5 water Cefamandole nafate compounds | 海南美大制药有限公司 | 2019-05-10 | — | — | CN | disclosed |
| CN-106565749-B | The method for promoting Cefamandole Nafate quality using three-dimensional column plate purification solvent | 华北制药河北华民药业有限责任公司 | 2018-10-09 | — | — | CN | disclosed |
| CN-106831821-A | 1/4 water Cefamandole nafate compounds | 海南灵康制药有限公司 | 2017-06-13 | — | — | CN | disclosed |
| CN-106699775-A | 1/5 water cefamandole sodium compound | 海南美大制药有限公司 | 2017-05-24 | — | — | CN | disclosed |
| CN-106565749-A | Method for improving quality of cemandil sodium by using three-dimensional column plate to purify solvent | 华北制药河北华民药业有限责任公司 | 2017-04-19 | — | — | CN | disclosed |
| CN-101321811-B | Cellulose acylate film, method of producing the same, cellulose derivative film, optically compensatory film using the same, optically-compensatory film incorporating polarizing plate, polarizing plate and liquid crystal display | FUJIFILM CORP. (JP) | 2011-12-21 | — | — | CN | disclosed |
| CN-101321811-A | Cellulose acylate film, method of producing the same, cellulose derivative film, optically compensatory film using the same, optically-compensatory film incorporating polarizing plate, polarizing plat | FUJIFILM CORP (JP) | 2008-12-10 | — | — | CN | disclosed |
| CN-1056374-C | Tricyclic diazepine vasopression antagonists | AMERICAN CYANAMID CO (US) | 2000-09-13 | — | — | CN | disclosed |
| CN-1039908-C | Tricyclic diaza * vasopressin antagonists and oxytocin antagonists | AMERICAN CYANAMID CO (US) | 1998-09-23 | — | — | CN | disclosed |