Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 14/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 14/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 11/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27264710 | 0.91 | UTS2R (0.37) | HCRTR1HCRTR2CYP3A4NPC1 | |
| Hydrochloric Acid SCHEMBL27305166 | 0.90 | UTS2R (0.36) | HCRTR1HCRTR2CYP3A4NPC1MEN1 | |
| SCHEMBL27264708 | 0.89 | L3MBTL1 (0.36) | NPC1RAB9ASMN1; SMN2MEN1POLB | |
| Hydrochloric Acid SCHEMBL27316772 | 0.88 | L3MBTL1 (0.35) | NPC1RAB9ASMN1; SMN2MEN1POLB | |
| SCHEMBL27329755 | 0.86 | MAPT (0.37) | HCRTR1HCRTR2CYP3A4NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL27296067 | 0.85 | MAPT (0.36) | HCRTR1HCRTR2CYP3A4NPC1RAB9A | |
| SCHEMBL27264157 | 0.85 | KDM4E (0.30) | ALDH1A1 | |
| SCHEMBL27264601 | 0.84 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL27264297 | 0.84 | HTR2A (0.36) | HCRTR1HCRTR2CYP3A4 | |
| Hydrochloric Acid SCHEMBL27501817 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1036004-C | Process for preparing analgesic carboxylic acid amide derivatives | SANKYO CO (JP) | 1997-10-01 | — | — | CN | disclosed |
| CN-1034731-C | Process for preparing analgesic carboxylic acid amide derivatives | SANKYO CO (JP) | 1997-04-30 | — | — | CN | disclosed |